Prabin Thapa

TL;DR: Long‐term, high‐dose UDCA therapy is associated with improvement in serum liver tests in PSC but does not improve survival and was associated with higher rates of serious adverse events.

TL;DR: The authors evaluated sarcopenia as a predictor of cancer‐specific survival (CSS) and overall survival (OS) among patients with urothelial cancer of the bladder undergoing radical cystectomy (RC).

TL;DR: An observational cohort study to assess the clinical characteristics, outcomes, and degree of undertreatment of mitral regurgitation in a community setting in Olmsted County, USA found that patients with a low comorbidity burden combined with favourable characteristics such as left-ventricular ejection fraction of 50% or higher incurred excess mortality.

TL;DR: This study provides Class IV evidence that azathioprine is effective for reducing relapse rates and improving EDSS and visual acuity scores in patients with NMO spectrum of disorders.

TL;DR: In this large cohort of patients with HFrEF, FTR was common and independently associated with PHTN, atrial-fibrillation and more severe heart failure presentation, and clinical trials should be directed at testing FTR treatment.