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John C. Cheville

Researcher at Mayo Clinic

Publications -  475
Citations -  38273

John C. Cheville is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Renal cell carcinoma & Nephrectomy. The author has an hindex of 90, co-authored 433 publications receiving 32806 citations. Previous affiliations of John C. Cheville include University of Rochester & Federal University of Ceará.

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Comprehensivemolecular characterization of clear cell renal cell carcinoma

Chad J. Creighton, +291 more
- 28 Aug 2013 - 
TL;DR: Remodelling cellular metabolism constitutes a recurrent pattern in ccRCC that correlates with tumour stage and severity and offers new views on the opportunities for disease treatment.
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Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Katherine A Hoadley, +738 more
- 05 Apr 2018 - 
TL;DR: Molecular similarities among histologically or anatomically related cancer types provide a basis for focused pan-cancer analyses, such as pan-gastrointestinal, Pan-gynecological, pan-kidney, and pan-squamous cancers, and those related by stemness features, which may inform strategies for future therapeutic development.
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An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: the SSIGN score.

TL;DR: In patients with clear cell renal cell carcinoma 1997 TNM stage, tumor size, nuclear grade and histological tumor necrosis were significantly associated with cancer specific survival, and a scoring system based on these features can be used to predict outcome.
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Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma.

TL;DR: It is demonstrated that there are significant differences in outcome and associations with outcome for the different histologic subtypes of RCC, highlighting the need for accurate subtyping.
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Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

W. Marston Linehan, +227 more
TL;DR: Type 1 and type 2 papillary renal-cell carcinomas were shown to be different types of renal cancer characterized by specific genetic alterations, with type 2 further classified into three individual subgroups on the basis of molecular differences associated with patient survival.