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Pranav Preman
Researcher at Katholieke Universiteit Leuven
Publications - 3
Citations - 28
Pranav Preman is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Astrocyte & Disease. The author has an hindex of 1, co-authored 3 publications receiving 10 citations.
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Journal ArticleDOI
Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaques.
Pranav Preman,Julia Tcw,Sara Calafate,An Snellinx,Maria Alfonso-Triguero,Nikky Corthout,Sebastian Munck,Dietmar Rudolf Thal,Alison Goate,Bart De Strooper,Bart De Strooper,Amaia M. Arranz +11 more
TL;DR: In this paper, a promising approach that consist of transplanting patient-derived and genetically modified astrocytes into the mouse brain to study human ASTs pathophysiology in the context of Alzheimer´s disease was described.
Journal ArticleDOI
Astrocytes in Alzheimer's Disease: Pathological Significance and Molecular Pathways.
Pranav Preman,Maria Alfonso-Triguero,Elena Alberdi,Alexei Verkhratsky,Alexei Verkhratsky,Amaia M. Arranz +5 more
TL;DR: A review of the origin, main functions, molecular and morphological features of astrocytes in physiological as well as pathological conditions related to Alzheimer´s disease is presented in this article.
Posted ContentDOI
Human iPSC-derived Astrocytes Transplanted into the Mouse Brain Display three Morphological Responses to Amyloid-β Plaques
Pranav Preman,Julia Tcw,Sara Calafate,An Snellinx,Maria Alfonso-Triguero,Nikky Corthout,Sebastian Munck,Dietmar Rudolf Thal,Alison Goate,Bart Destrooper,Bart Destrooper,Amaia M. Arranz +11 more
TL;DR: A chimeric model transplanting human induced pluripotent stem cell (hiPSC)-derived glia progenitors into neonatal brains of immunodeficient mice has great potential to analyze the role of patient-derived and genetically modified astroglia in Alzheimer9s disease.