P
Prasanta Kumar Dey
Researcher at Institute of Medical Sciences, Banaras Hindu University
Publications - 22
Citations - 1477
Prasanta Kumar Dey is an academic researcher from Institute of Medical Sciences, Banaras Hindu University. The author has contributed to research in topics: Blood–brain barrier & Cerebral blood flow. The author has an hindex of 19, co-authored 22 publications receiving 1436 citations.
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Increased blood-brain barrier permeability following acute short-term swimming exercise in conscious normotensive young rats
TL;DR: Results suggest that short-term FS increases BBB permeability in specific brain regions, and this increased permeability appears to be mediated through serotonin via 5-HT2 receptors.
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Changes in blood-brain barrier and cerebral blood flow following elevation of circulating serotonin level in anesthetized rats
TL;DR: A hypothesis is put forward that serotonin after binding to its receptor in the cerebral vessels stimulates prostaglandin which either directly or by means of cyclic adenosine monophosphate causes an increased vesicular transport across the endothelial cells and thus an extravasation of tracer substances in the brain.
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Influence of long-term immobilization stress on regional blood-brain barrier permeability, cerebral blood flow and 5-HT level in conscious normotensive young rats
TL;DR: Eight hours immobilization stress in young rats has increased the blood-brain barrier (BBB) permeability in 12 out of 14 brain regions studied, and the increased BBB permeability and increased 5-HT levels were prevented by pretreatment with p-CPA, indomethacin and diazepam.
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Influence of long-term acute heat exposure on regional blood-brain barrier permeability, cerebral blood flow and 5-HT level in conscious normotensive young rats
TL;DR: Exposure of conscious young rats to 4 h heat stress at 38 degrees C in B.O.D. incubator was associated with increased blood-brain barrier permeability in 14 brain regions studied, and a correlation was observed with increased plasma and brain 5-hydroxytryptamine levels.
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Probable involvement of serotonin in the increased permeability of the blood-brain barrier by forced swimming. An experimental study using Evans blue and 131I-sodium tracers in the rat.
TL;DR: 5-HT plays an important role in the breakdown of BBB permeability in FS, this effect of 5-HT on BBB porousness is mediated by 5- HT2 receptors, and the FS induced increase in BBb permeability is age dependent.