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Showing papers in "Brain Research in 1987"


Journal ArticleDOI
TL;DR: The adult spinal cat preparation is considered as a useful model to study the influence of different types of training and of different drugs or other treatments in the process of locomotor recovery after injury to the spinal cord.

843 citations


Journal ArticleDOI
TL;DR: N-Methylaspartate receptors appear to contribute to the wind-up, but not the initial response, of class 2 neurones in the rat, while Iontophoretic or intravenous ketamine had no consistent effect on theInitial response but consistently reduced wind- up.

648 citations


Journal ArticleDOI
TL;DR: The distribution of Ca2+-binding protein, parvalbumin (PV), containing neurons and their colocalization with glutamic acid decarboxylase (GAD) were studied in the rat hippocampus and dentate gyrus using immunohistochemistry.

530 citations


Journal ArticleDOI
TL;DR: The results suggest that different pathways are modulated when attention is deployed to different regions of the visual fields, and suggest that the special role of the right hemisphere in spatial attention may be limited to analysis of information in the visual periphery.

517 citations


Journal ArticleDOI
TL;DR: Fast spiking cells in the CA1 region of the rat hippocampus were revealed as gamma-aminobutyric acid (GABA)ergic non-pyramidal cells containing the calcium-binding protein parvalbumin by intracellular injection of Lucifer yellow in vitro in combination with postembedding parValbumin immunohistochemistry.

495 citations


Journal ArticleDOI
TL;DR: NGF and central catecholaminergic neuronal function, NGF-induced alteration in adrenergic CNS function, and retrograde transport of NGF in Adrenergic pathways are studied.

485 citations


Journal ArticleDOI
TL;DR: Measurements of DA release add further support to the hypothesis that amphetamine-induced stereotypy and locomotion are mediated via DA released in striatum and n.

411 citations


Journal ArticleDOI
TL;DR: The results indicate that not only are there more synapses per neuron in the visual cortex of rats from more complex environments but also that the brain appears to adjust to the metabolic requirements of its synapses or neurons, in terms of vascular, mitochondrial and glial support.

409 citations


Journal ArticleDOI
TL;DR: 125I-Melatonin was used to localize and characterize the melatonin receptor sites in the rat hypothalamus and revealed that displaceable 125I-melatonin binding occurred in suprachiasmatic nuclei and median eminence only.

399 citations


Journal ArticleDOI
TL;DR: The results suggest that 5-HT neurons innervate both dopaminergic and non-dopaminergic neurons in the VTA and may influence mesocortical and mesolimbic efferent systems through synaptic as well as non-synaptic mechanisms.

383 citations


Journal ArticleDOI
TL;DR: It is suggested that in the rat spinal dorsal horn, CGRP potentiates the release of substance P from the primary afferent terminal and promotes the transmission of nociceptive information induced by mechanical noxious stimuli.

Journal ArticleDOI
TL;DR: The correlation of the transport data, the autoradiography, and the HPLC analysis support the model that brain insulin originates from blood via receptor-mediated transport of the peptide at the blood-brain barrier.

Journal ArticleDOI
TL;DR: Phacl ofen may be useful in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact.

Journal ArticleDOI
TL;DR: It is suggested that, for most rats, LTP elicited by theta pattern stimulation is stable until such time that stimulation-recording arrangements begin to deteriorate, which is about the point at which the responses began their rapid decline.

Journal ArticleDOI
TL;DR: Evaluating the similarities and differences in relation to the olfactory bulb suggests that EEG patterns that manifest differing states of the visual cortex may also be accessible with scalp electrodes.

Journal ArticleDOI
TL;DR: It appears that age-related changes are not consistently found on measures such as the activity of ChAT or the content of ACh in these regions, basal levels of A Ch release in cortex, and the number of cholinergic neurons in the basal forebrain.

Journal ArticleDOI
TL;DR: The interaction of the 'neurosteroid', pregnenolone-sulfate (PS), with the GABA/benzodiazepine/chloride ionophore receptor complex was investigated in rat brain subcellular preparations, suggesting the regulation of GABAergic neurotransmission by various neurosteroids may be an important mechanism for controlling neuronal excitability.

Journal ArticleDOI
TL;DR: Comparison of young vs aged cases indicate that aging does not appear to have a profound influence on cortical innervation patterns, at least as studied with the PHA-L method.

Journal ArticleDOI
TL;DR: Evidence is presented that neuronal activity in the monkey inferomedial temporal cortex reflects memory for the previous occurrence of visual stimuli, and suggests that the inferomedIAL temporal cortex plays a central role in processes necessary for recognition memory.

Journal ArticleDOI
TL;DR: Increased susceptibility to the convulsant action of pilocarpine was characterized by a shortened latency for behavioral and electrographic signs, and an increased severity of seizures relative to older and younger rats.

Journal ArticleDOI
TL;DR: An activating effect of NPY is demonstrated on the pituitary-adrenocortical axis both in conscious and anaesthetized rats which may reflect the anatomical relationship between NPY fibres and CRF neurones in the PVN.

Journal ArticleDOI
TL;DR: Data indicate that the conditioned response pathway, and sites of plasticity, for eyelid conditioning are spared by decerebration and are contained within the brainstem and cerebellum.

Journal ArticleDOI
TL;DR: The timing and pattern of the response elicited by electrical stimulation of the amygdala in the awake but not the anesthetized rat closely corresponds with that evoked by an acoustic conditioned emotional stimulus.

Journal ArticleDOI
TL;DR: The striatum of the mammalian forebrain is composed of two complementary functional compartments, the patches and the matrix, and it is found that the earliest neurons to leave the mitotic cycle were restricted to the patch compartment.

Journal ArticleDOI
TL;DR: The staining pattern observed in the brain may indicate that GSH is primarily localized to non-neuronal elements, such as glia, and/or in axons and nerve terminals.

Journal ArticleDOI
TL;DR: It is demonstrated that large aspiny neurons, containing the enzyme acetylcholinesterase (AChE), are relatively preserved in the caudate nucleus and putamen in Huntington's disease (HD).

Journal ArticleDOI
TL;DR: These findings represent the first demonstration that PKC inhibitors prevent persistence of potentiation and suggest thatPKC regulates the persistence of synaptic enhancement beginning after its onset, and that PKc's role decreases with time after the induction of enhancement.

Journal ArticleDOI
TL;DR: A pure cortical neuronal culture free of glial cells, grown in a serum-free environment, provides a new system for investigating neuronal development and function in the complex mammalian central nervous system.

Journal ArticleDOI
TL;DR: The results indicated that SNR contains two electrophysiologically different types of neurons, and that both type of neurons receive monosynaptic EPSPs from STH and IPSPs from areas rostral to STH.

Journal ArticleDOI
TL;DR: Clear strain differences were found for performance on the third day of training, which correlated very strongly with the size of the hippocampal intra- and infrapy ramidal mossy fibre terminal fields in iip-MF.