P
Premalatha Balachandran
Researcher at University of Mississippi
Publications - 22
Citations - 995
Premalatha Balachandran is an academic researcher from University of Mississippi. The author has contributed to research in topics: Immune system & Cancer. The author has an hindex of 12, co-authored 22 publications receiving 834 citations.
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Cancer—an ayurvedic perspective
TL;DR: Review of literature on anticancer drugs of plant origin revealed identification of newer ayurvedic drugs that are not mentioned in the ancient texts, and details of experimental and clinical studies conducted on single and compound ayuvedic preparations for their anticancer efficacy strongly emphasize ayur Vedic therapy as a scientifically driven one and not simply unconventional.
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Structure activity relationships of aristolochic acid analogues: Toxicity in cultured renal epithelial cells
Premalatha Balachandran,Feng Wei,Feng Wei,Rui-Chao Lin,Rui-Chao Lin,Ikhlas A. Khan,Ikhlas A. Khan,David S. Pasco,David S. Pasco +8 more
TL;DR: In this paper, a series of aristolochic acid derivatives were analyzed for their nephrotoxic potential using the neutral red dye exclusion assay in cultures of LLC-PK 1 cells.
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Toll-like receptor 2-dependent activation of monocytes by Spirulina polysaccharide and its immune enhancing action in mice.
TL;DR: Light is shed on how Immulina activates cells of the innate immune system and suggests that oral consumption of this polysaccharide can enhance components within both the mucosal and systemic immune systems.
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The majority of in vitro macrophage activation exhibited by extracts of some immune enhancing botanicals is due to bacterial lipoproteins and lipopolysaccharides
Nirmal Pugh,Hemlata Tamta,Premalatha Balachandran,Xiangmei Wu,J'Lynn Howell,Franck E. Dayan,David S. Pasco +6 more
TL;DR: It is indicated that the majority of the in vitro macrophage activating properties in extracts from these botanicals can be attributed to the presence of lipoproteins and lipopolysaccharides derived from bacteria and that bacterial endophytes may be a significant source of these components.
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Melanin: dietary mucosal immune modulator from Echinacea and other botanical supplements.
Nirmal Pugh,Premalatha Balachandran,Hemant Lata,Franck E. Dayan,Vaishali C. Joshi,Erdal Bedir,Toshiaki Makino,Rita M. Moraes,Ikhlas A. Khan,David S. Pasco +9 more
TL;DR: It is shown that melanin is a previously unrecognized immunostimulatory compound that is a major component of botanicals traditionally used to enhance immune function and will allow further characterization of botanical products and advances the understanding of the basis for their traditional use.