P
Puja Garg
Researcher at Central Drug Research Institute
Publications - 5
Citations - 229
Puja Garg is an academic researcher from Central Drug Research Institute. The author has contributed to research in topics: Nitric oxide synthase & Amino acid. The author has an hindex of 4, co-authored 5 publications receiving 205 citations.
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Journal ArticleDOI
Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat.
TL;DR: First evidence of effectiveness of curcumin when given 4h post-ischemia in the rat thromboembolic stroke models is shown, as it reduces infarct volume, ameliorates the sensory motor function and significantly attenuated the nitrosative stress.
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Neuroprotective efficacy and therapeutic window of curcuma oil: in rat embolic stroke model
TL;DR: It is demonstrated that iNOS-derived NO produced during ischemia injury was crucial for the up-regulation of ischemic injury targets and down-regulates these targets this coincided with an increased survival rate of neurons.
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Amino acid-based enantiomerically pure 3-substituted 1,4-benzodiazepin-2-ones: a new class of anti-ischemic agents.
Jitendra Kumar Mishra,Puja Garg,Preeti Dohare,Ashutosh Kumar,Mohammad Imran Siddiqi,Madhur Ray,Gautam Panda +6 more
TL;DR: Treatment with compounds decreasing apoptosis and increasing neuronal viability decreased the apoptotic neuronal number, however increased the neuronal viability, which could protect neurons from the ischemic injury.
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The neuronal apoptotic death in global cerebral ischemia in gerbil: important role for sodium channel modulator.
Manoja K. Brahma,Preeti Dohare,Saurabh Varma,Srikanta Kumar Rath,Puja Garg,Prasanta Kumar Biswal,Piyali Dhar Chowdhury,Madhur Ray +7 more
TL;DR: This report is the first to highlight the involvement of the voltage‐sensitive Na+ channel in possibly regulating in part NO system and apoptosis in a cytochrome c–dependent manner in global ischemia in the gerbil, and thus warrants further investigation.