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Qian Huang

Researcher at University of Texas MD Anderson Cancer Center

Publications -  40
Citations -  3563

Qian Huang is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Photothermal therapy & Chemistry. The author has an hindex of 20, co-authored 34 publications receiving 3184 citations. Previous affiliations of Qian Huang include University of Texas Health Science Center at Houston.

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Copper sulfide nanoparticles for photothermal ablation of tumor cells

TL;DR: Owing to their unique optical property, small size, low cost of production and low cytotoxicity, CuS nanoparticles are promising new nanomaterials for cancer photothermal ablation therapy.
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Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice

TL;DR: 20-nm AuNPs coated with TA-terminated PEG(5000) are promising potential drug delivery vehicles and diagnostic imaging agents and show significantly higher tumor uptake and extravasation from the tumor blood vessels.
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Copper sulfide nanoparticles as a new class of photoacoustic contrast agent for deep tissue imaging at 1064 nm.

TL;DR: Use of semiconductor copper sulfide nanoparticles (CuS NPs) for PAT with an Nd:YAG laser at a wavelength of 1064 nm allowed visualization of mouse brain after intracranial injection, rat lymph nodes 12 mm below the skin after interstitial injection, and CuS NP-containing agarose gel embedded in chicken breast muscle at a depth of ~5 cm.
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Tumor Site–Specific Silencing of NF-κB p65 by Targeted Hollow Gold Nanosphere–Mediated Photothermal Transfection

TL;DR: Near-IR (NIR) light-inducible NF-kappaB downregulation through folate receptor-targeted hollow gold nanospheres carrying siRNA recognizing NF- kappaB p65 subunit is reported, which could effectively sensitize the tumor to chemotherapeutic agents.
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Targeted photothermal ablation of murine melanomas with melanocyte-stimulating hormone analog-conjugated hollow gold nanospheres.

TL;DR: NDP-MSH-PEG-HAuNS have the potentials to mediate targeted photothermal ablation of melanoma and are confirmed by histologic and positron emission tomography evaluation.