다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

XI. STRATEGIES FOR IMPROVING DIABETES CARE D iabetes is a chronic illness that requires continuing medical care and patient self-management education to prevent acute complications and to reduce the risk of long-term complications. Diabetes care is complex and requires that many issues, beyond glycemic control, be addressed. A large body of evidence exists that supports a range of interventions to improve diabetes outcomes. These standards of care are intended to provide clinicians, patients, researchers, payors, and other interested individuals with the components of diabetes care, treatment goals, and tools to evaluate the quality of care. While individual preferences, comorbidities, and other patient factors may require modification of goals, targets that are desirable for most patients with diabetes are provided. These standards are not intended to preclude more extensive evaluation and management of the patient by other specialists as needed. For more detailed information, refer to Bode (Ed.): Medical Management of Type 1 Diabetes (1), Burant (Ed): Medical Management of Type 2 Diabetes (2), and Klingensmith (Ed): Intensive Diabetes Management (3). The recommendations included are diagnostic and therapeutic actions that are known or believed to favorably affect health outcomes of patients with diabetes. A grading system (Table 1), developed by the American Diabetes Association (ADA) and modeled after existing methods, was utilized to clarify and codify the evidence that forms the basis for the recommendations. The level of evidence that supports each recommendation is listed after each recommendation using the letters A, B, C, or E.

Standards of Medical Care in Diabetes

Prospective Cohort Study

EVOLUTION: Of Mice . . .

The study group.

An elevated serum pigment epithelium-derived factor level strongly correlates with insulin resistance in PCOS women.

/pdf/serum-pigment-epithelium-derived-factor-is-elevated-in-women-17v398eqyx.pdf

Serum pigment epithelium-derived factor is elevated in women with polycystic ovary syndrome and correlates with insulin resistance.

Aims
Adult-onset autoimmune diabetes is prevalent in China, in contrast to childhood-onset type 1 diabetes mellitus. Islet autoantibodies are the most important immune biomarkers to diagnose autoimmune diabetes. We assayed four different islet autoantibodies in recently diagnosed adult non-insulin-requiring diabetes Chinese subjects to investigate the best antibody assay strategy for the correct diagnosis of these subjects.

/pdf/glutamic-acid-decarboxylase-autoantibodies-are-dominant-but-3eqy58w52w.pdf

Glutamic acid decarboxylase autoantibodies are dominant but insufficient to identify most Chinese with adult-onset non- insulin requiring autoimmune diabetes: LADA China study 5

Bisphenol A (BPA) is associated with diabetes and cardiovascular diseases The aim of our study was to evaluate whether serum BPA could predict the progression of chronic kidney disease (CKD) in patients with type 2 diabetes (T2D) In this prospective study, a total of 121 patients with T2D and estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/173 m2 were followed up for 6 years The baseline values of serum BPA were measured Renal function was measured as eGFR calculated by the Chronic Kidney Disease Epidemiology Collaboration creatinine–cystatin C equation Development of CKD was defined as eGFR < 60 mL/min/173 m2 at the last follow-up Regression models were used to analyze the associations of serum BPA with the change in eGFR and the risk of CKD development Baseline serum BPA concentration was 040 (017, 140) ng/mL Duration of T2D, baseline waist circumference, systolic blood pressure, diastolic blood pressure, fasting plasma glucose, and serum BPA level were significantly negatively associated with the annual change and percentage change in eGFR After adjusting for clinical factors, baseline serum BPA level had a significant negative association with the annual change in eGFR (β = −0371, P < 0001) and percentage change in eGFR (β = −0391, P = <0001) Multivariate logistic regression analysis showed that patients with high levels of serum BPA exhibited about a sevenfold increased risk of developing CKD compared to patients with low levels of serum BPA [odds ratio (OR) 665 (95 % CI 147, 3004), P = 0014] Serum BPA may be a predictor of CKD in patients with T2D

Serum bisphenol A and progression of type 2 diabetic nephropathy: a 6-year prospective study.

Objective:Hypertensive nephropathy is one of the major causes of chronic kidney disease (CKD). Bisphenol A (BPA) is associated with elevated blood pressure and urinary albuminuria. The aim of this study is to evaluate the association between serum BPA with the progression of CKD in patients with pri

Serum bisphenol A as a predictor of chronic kidney disease progression in primary hypertension: a 6-year prospective study.

In this study, we assessed whether the apolipoprotein B/apolipoprotein A1 ratio (ApoB/ApoA1) is related to metabolic syndrome (MS) and its components in an urban Chinese population. A total of 709 community residents were enrolled. Metabolic syndrome was defined according to the International Diabetes Federation definition in 2005. The high ApoB/ApoA1 group was defined as the gender-specific upper quartile of the ApoB/ApoA1 ratio. Insulin resistance (IR) was defined as the upper quartile of Homa-IR. The ApoB/ApoA1 ratio was significantly higher in subjects with MS, compared to those without (p < 0.05). After adjusting for age and gender, subjects with MS (odds ratio [OR] = 3.5) or IR (OR = 2.3) were more likely to be in the high ApoB/ApoA1 group. The ApoB/ApoA1 ratio increased significantly as the number of MS components increased (p < 0.05). Taken together, these data demonstrate that the ApoB/ApoA1 ratio is strongly associated with MS and its components in an urban Chinese population.

Qifu Li

Papers

Serum pigment epithelium-derived factor is elevated in women with polycystic ovary syndrome and correlates with insulin resistance.

Glutamic acid decarboxylase autoantibodies are dominant but insufficient to identify most Chinese with adult-onset non- insulin requiring autoimmune diabetes: LADA China study 5

Serum bisphenol A and progression of type 2 diabetic nephropathy: a 6-year prospective study.

Serum bisphenol A as a predictor of chronic kidney disease progression in primary hypertension: a 6-year prospective study.

The ApoB/ApoA1 ratio is associated with metabolic syndrome and its components in a Chinese population.