Qifu Li

TL;DR: This study demonstrates the efficacy of ADRR as a screening test for PA, however, as antihypertensive drugs can interfere with the interpretation of AD RR, it is recommended to interrupt therapy or at least replace with analogues that do not significantly affect the ADRR value.

TL;DR: Investigation of the effect of metformin, a widely used agent to improve IR, on PEDF production both in vivo and in vitro found it inhibits the expression and secretion of PEDf in fat and liver via promoting AMPK phosphorylation, which is closely associated with IR improvement.

TL;DR: Serum cfDNA is closely associated with DKD, and it might be a predictor of DKD progression in patients with type 2 diabetes, after adjustment of age, gender, body mass index, fast plasma glucose, smoking, triglycerides, total cholesterol, duration of diabetes, systolic blood pressure, diabetic retinopathy, eGFR, high sensitivity C-reactive protein, angiotensin receptor blocker/ACE inhibitor usage.

TL;DR: Younger age at diabetes diagnosis, higher baseline insulin sensitivity, and lower glucose levels after insulin treatment significantly favored a 2-year glycemic remission, attributed to both improved insulin sensitivity and enhanced β-cell function after short-term intensive insulin treatment.

TL;DR: Patients with primary aldosteronism should have a low-dose overnight dexamethasone suppression test to screen for hypercortisolism and make sure of the nidus of aldosterone and cortisol secretion is crucial for the therapy of patients with primaryAldoster onism and subclinical Cushing’s syndrome.