Q
Qin Dong
Researcher at University of Toronto
Publications - 7
Citations - 451
Qin Dong is an academic researcher from University of Toronto. The author has contributed to research in topics: Internal medicine & Dysfunctional family. The author has an hindex of 4, co-authored 5 publications receiving 436 citations. Previous affiliations of Qin Dong include University Health Network.
Papers
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Journal ArticleDOI
Neutrophil-mediated epithelial injury during transmigration: role of elastase
Hedy Ginzberg,Vera Cherapanov,Qin Dong,André M. Cantin,Christopher A. McCulloch,Patrick Shannon,Gregory P. Downey +6 more
TL;DR: Spatially delimited disruption of epithelial junctional complexes with focal loss of E-cadherin, beta-catenin, and zonula occludens 1 was observed adjacent to clusters of transmigrating neutrophils.
Journal ArticleDOI
Regulation of neutrophil activation in acute lung injury.
Journal ArticleDOI
Deficiency of Src homology 2-containing phosphatase 1 results in abnormalities in murine neutrophil function: studies in motheaten mice.
Joshua Kruger,Jeffrey R. Butler,Vera Cherapanov,Vera Cherapanov,Qin Dong,Qin Dong,Hedy Ginzberg,Hedy Ginzberg,Anand Govindarajan,Anand Govindarajan,Sergio Grinstein,Katherine A. Siminovitch,Katherine A. Siminovitch,Katherine A. Siminovitch,Gregory P. Downey,Gregory P. Downey +15 more
TL;DR: A significant role for SHP-1 is indicated in modulating the tyrosine phosphorylation-dependent signaling pathways that regulate neutrophil microbicidal functions.
Journal Article
Negative Regulation of Myeloid Cell Proliferation and Function by the SH2 Domain-Containing Tyrosine Phosphatase-1
Qin Dong,Katherine A. Siminovitch,Katherine A. Siminovitch,Lea Fialkow,Takeyasu Fukushima,Gregory P. Downey +5 more
TL;DR: The results suggest that SHP-1 exerts an important negative regulatory influence on cell proliferation and activation while promoting spontaneous cell death in myeloid cells.