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Qing-Qing Xu
Researcher at Harvard University
Publications - 6
Citations - 341
Qing-Qing Xu is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 1 publications receiving 306 citations.
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Journal ArticleDOI
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
Jeffrey C. Lee,Jeffrey C. Lee,Igor Vivanco,Rameen Beroukhim,Rameen Beroukhim,Julie H. Y Huang,Whei Feng,Whei Feng,Ralph M. Debiasi,Ralph M. Debiasi,Koji Yoshimoto,J. King,Phioanh L. Nghiemphu,Yuki Yuza,Qing-Qing Xu,Heidi Greulich,Heidi Greulich,Roman K. Thomas,Roman K. Thomas,J. Guillermo Paez,J. Guillermo Paez,Timothy C. Peck,Timothy C. Peck,David Linhart,David Linhart,Karen A. Glatt,Gad Getz,Robert C. Onofrio,Liuda Ziaugra,Ross L. Levine,Stacey Gabriel,Tomohiro Kawaguchi,Keith O'Neill,Haumith Khan,Linda M. Liau,Stanley F. Nelson,P. Nagesh Rao,Paul S. Mischel,Russell O. Pieper,Timothy F. Cloughesy,Daniel J. Leahy,William R. Sellers,William R. Sellers,Charles L. Sawyers,Matthew Meyerson,Matthew Meyerson,Ingo K. Mellinghoff +46 more
TL;DR: The results suggest extracellular missense mutations as a novel mechanism for oncogenic EGFR activation and may help identify patients who can benefit from EGFR kinase inhibitors for treatment of glioblastoma.
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Patchouli alcohol ameliorates the learning and memory impairments in an animal model of Alzheimer's disease via modulating SIRT1.
TL;DR: In this article , the authors investigated the anti-AD effects of patchouli alcohol (PA) in an animal model of AD and to elucidate the underlying molecular mechanisms, which showed that PA could significantly ameliorate the learning and memory deficits induced by STZ in rats.
Journal ArticleDOI
Sulforaphene, a CDK5 Inhibitor, attenuates cognitive deficits in a transgenic mouse model of Alzheimer's disease via reducing Aβ Deposition, tau hyperphosphorylation and synaptic dysfunction.
TL;DR: Wang et al. as mentioned in this paper evaluated the cognitive deficits improving effects of Sulforaphene (SF) on in TgCRND8 mice and to elucidate the underlying molecular mechanisms.
Journal ArticleDOI
Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer’s disease via modulating neuropathology and gut microbiota through suppressing C/EBPβ/AEP pathway
TL;DR: Wang et al. as mentioned in this paper investigated the therapeutic effects of patchouli alcohol against Alzheimer's disease using the TgCRND8 transgenic AD mouse model, and explored the underlying mechanisms targeting CCAAT/enhancer-binding protein β/asparagine endopeptidase (C/EBPβ/AEP) signaling pathway.
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Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion
Yan-Feng Huang,Xie Zhang,Qionghui Huang,Yao-Xing Dou,Chang Qu,Qing-Qing Xu,Qiuju Yuan,Yan-Fang Xian,Zhi-Xiu Lin +8 more
TL;DR: In this article , the authors investigated whether quercetin (QCN) could improve motor function recovery after C5-7 ventral root avulsion and C6 reimplantation in a rat model of BPA.