T
Timothy C. Peck
Researcher at Harvard University
Publications - 3
Citations - 1777
Timothy C. Peck is an academic researcher from Harvard University. The author has contributed to research in topics: Cyclin-dependent kinase 8 & Epidermal growth factor receptor. The author has an hindex of 3, co-authored 3 publications receiving 1717 citations. Previous affiliations of Timothy C. Peck include Broad Institute & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
Ingo K. Mellinghoff,Maria Y. Wang,Igor Vivanco,Daphne A. Haas-Kogan,Shaojun Zhu,Ederlyn Q. Dia,Kan V. Lu,Koji Yoshimoto,Julie H. Y Huang,Dennis J. Chute,Bridget L. Riggs,Steve Horvath,Linda M. Liau,Webster K. Cavenee,P. Nagesh Rao,Rameen Beroukhim,Rameen Beroukhim,Rameen Beroukhim,Timothy C. Peck,Timothy C. Peck,Timothy C. Peck,Jeffrey C. Lee,Jeffrey C. Lee,Jeffrey C. Lee,William R. Sellers,William R. Sellers,William R. Sellers,David Stokoe,Michael D. Prados,Timothy F. Cloughesy,Charles L. Sawyers,Paul S. Mischel +31 more
TL;DR: Coexpression of EGFRvIII and PTEN by glioblastoma cells is associated with responsiveness to EGFR kinase inhibitors, and effects of the molecular abnormalities in vitro are identified.
Journal ArticleDOI
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
Jeffrey C. Lee,Jeffrey C. Lee,Igor Vivanco,Rameen Beroukhim,Rameen Beroukhim,Julie H. Y Huang,Whei Feng,Whei Feng,Ralph M. Debiasi,Ralph M. Debiasi,Koji Yoshimoto,J. King,Phioanh L. Nghiemphu,Yuki Yuza,Qing-Qing Xu,Heidi Greulich,Heidi Greulich,Roman K. Thomas,Roman K. Thomas,J. Guillermo Paez,J. Guillermo Paez,Timothy C. Peck,Timothy C. Peck,David Linhart,David Linhart,Karen A. Glatt,Gad Getz,Robert C. Onofrio,Liuda Ziaugra,Ross L. Levine,Stacey Gabriel,Tomohiro Kawaguchi,Keith O'Neill,Haumith Khan,Linda M. Liau,Stanley F. Nelson,P. Nagesh Rao,Paul S. Mischel,Russell O. Pieper,Timothy F. Cloughesy,Daniel J. Leahy,William R. Sellers,William R. Sellers,Charles L. Sawyers,Matthew Meyerson,Matthew Meyerson,Ingo K. Mellinghoff +46 more
TL;DR: The results suggest extracellular missense mutations as a novel mechanism for oncogenic EGFR activation and may help identify patients who can benefit from EGFR kinase inhibitors for treatment of glioblastoma.
Journal ArticleDOI
Practicing emergency physicians report performing well on most emergency medicine milestones.
Timothy C. Peck,Timothy C. Peck,Nicole M. Dubosh,Nicole M. Dubosh,Carlo L. Rosen,Carlo L. Rosen,Carrie Tibbles,Carrie Tibbles,Jennifer Pope,Jonathan Fisher,Jonathan Fisher +10 more
TL;DR: Although a majority of EM attendings reported meeting Level 4 milestones, many felt they did not meet Level 4 criteria, and report less perceived competence in ultrasound skills than other milestones.