Q
Qinghao Zhou
Researcher at University of Science and Technology of China
Publications - 16
Citations - 270
Qinghao Zhou is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 3, co-authored 9 publications receiving 109 citations.
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Integrated block copolymer prodrug nanoparticles for combination of tumor oxidative stress amplification and ROS-responsive drug release.
TL;DR: In this article, the authors developed integrated nanoparticles to remold tumor microenvironment via specific amplification of the tumor oxidative stress and simultaneously realize ROS-responsive drug release, which has been frequently explored as the specific stimulus to trigger drug release.
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Ferrocene-containing polymersome nanoreactors for synergistically amplified tumor-specific chemodynamic therapy.
Yuheng Wang,Shuang Zhang,Jingbo Wang,Qinghao Zhou,Jean Felix Mukerabigwi,Wendong Ke,Nannan Lu,Zhishen Ge +7 more
TL;DR: In this paper, the authors presented ferrocene-containing responsive polymersome nanoreactors via loading glucose oxidase (GOD) and hypoxia-activable prodrug tirapazamine (TPZ) in the inner aqueous cavities.
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Length effect of stimuli-responsive block copolymer prodrug filomicelles on drug delivery efficiency
Wendong Ke,Nannan Lu,Abd Al-Wali Mohammed M. Japir,Qinghao Zhou,Longchang Xi,Yuheng Wang,Debabrata Dutta,Min Zhou,Yueyin Pan,Zhishen Ge +9 more
TL;DR: Among them, SFMs are demonstrated to be internalized into cells most efficiently at pH 6.5 due to larger interaction areas with cell membranes relative to SMs, and show prolonged blood circulation similar toSMs as well as deepest tumor penetration and best antitumor efficacy among the three nanoparticles.
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Hypoxia-responsive block copolymer polyprodrugs for complementary photodynamic-chemotherapy
TL;DR: In this paper, a block copolymer polyprodrug consisting of polyethylene glycol (PEG) and Copolymerized segments of nitroimidazole-linked camptothecin (CPT) methacrylate and 5,10,15,20-tetraphenylporphyrin (TPP)-containing methacelate monomers for complementary photodynamic-chemotherapy was presented.
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Protein-Delivering Nanocomplexes with Fenton Reaction-Triggered Cargo Release to Boost Cancer Immunotherapy.
TL;DR: The nanocomplexes with Fenton reaction-triggered protein release show great potentials to improve the immunotherapeutic efficacy of ICB via combination with CDT.