Qinrui Li

TL;DR: The bidirectional interactions between the central nervous system and the gastrointestinal tract (brain-gut axis) and the role of the gut microbiota in the central nerve system (CNS) and ASD are reviewed and microbiome-mediated therapies might be a safe and effective treatment for ASD.

TL;DR: Based on the evidence presented in this review, individuals withFXS and comorbid ASD have more severe behavioral problems than individuals with FXS alone, however, patients with FXs and comerbid ASD exhibit less severe impairments in the social and communication symptoms than patients with nonsyndromic ASD.

TL;DR: The findings suggest that intestinal microbiota is different between the NT children and the ASD children with or without GI problems, and in combination with ABA training, probiotics treatment can bring more benefit to ASD children.

TL;DR: Investigation of time-dependent changes in autophagy, apoptosis and neuronal morphology in developing brain of epilepsy model rats indicates that autophophagy starts before apoptosis in rats with epilepsy, demonstrating a potential role of autophagic in epilepsy-induced neuronal loss in developingbrain.

TL;DR: Results show that recurrent FS may induce injury of hippocampal cell by interfering with AKT activation through ERS-mediated up-regulation of TRIB3.