Q
Qizhi Zhang
Researcher at University of Medicine and Dentistry of New Jersey
Publications - 2
Citations - 139
Qizhi Zhang is an academic researcher from University of Medicine and Dentistry of New Jersey. The author has contributed to research in topics: Muscle hypertrophy & Afterload. The author has an hindex of 2, co-authored 2 publications receiving 135 citations. Previous affiliations of Qizhi Zhang include Rutgers University.
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Journal ArticleDOI
Mechanism of Enhanced Cardiac Function in Mice with Hypertrophy Induced by Overexpressed Akt
Young Kwon Kim,Song Jung Kim,Atsuko Yatani,Yanhong Huang,Germana Castelli,Dorothy E. Vatner,Jing Liu,Qizhi Zhang,Gissela Diaz,Renata Zieba,Jill Thaisz,Alessandra Drusco,Carlo M. Croce,Junichi Sadoshima,Gianluigi Condorelli,Stephen F. Vatner +15 more
TL;DR: Myocytes from mice with overexpressed Akt demonstrated enhanced contractility and relaxation, Fura-2 Ca2- transients, and Ca2+ channel currents, and increased protein expression of SERCA2a plays an important role in mediating enhanced LV function by Akt.
Journal ArticleDOI
Neurally-mediated increase in calcineurin activity regulates cardiac contractile function in absence of hypertrophy.
Joan Li,Joan Li,Atsuko Yatani,Song Jung Kim,Gen Takagi,Keiichi Irie,Qizhi Zhang,Vijaya Karoor,Chull Hong,Guiping Yang,Junichi Sadoshima,Christophe Depre,Dorothy E. Vatner,Malcolm J. West,Stephen F. Vatner +14 more
TL;DR: Calcineurin can be activated in the heart through a neural stimulus, which induces alterations in Ca(2+) currents and contractility, which occurs in the absence of myocyte hypertrophy, electrophysiological changes in action potential, and K(+) channel currents.