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Quan Le Tran
Researcher at Shenyang Pharmaceutical University
Publications - 31
Citations - 1411
Quan Le Tran is an academic researcher from Shenyang Pharmaceutical University. The author has contributed to research in topics: Caesalpinia sappan & Xanthine oxidase. The author has an hindex of 19, co-authored 29 publications receiving 1305 citations.
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Antiproliferative activity of Vietnamese medicinal plants.
Jun-ya Ueda,Yasuhiro Tezuka,Arjun H. Banskota,Quan Le Tran,Qui Kim Tran,Yuko Harimaya,Ikuo Saiki,Shigetoshi Kadota +7 more
TL;DR: Characteristic morphological change and DNA fragmentation indicated the antiproliferative activity to be due to the induction of apoptosis.
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Xanthine Oxidase Inhibitory Activity of Vietnamese Medicinal Plants
Mai Thanh Thi Nguyen,Suresh Awale,Yasuhiro Tezuka,Quan Le Tran,Hiroshi Watanabe,Shigetoshi Kadota +5 more
TL;DR: Among 288 extracts, prepared from 96 medicinal plants used in Vietnamese traditional medicine to treat gout and related symptoms, 188 demonstrated xanthine oxidase (XO) inhibitory activity at 100 microg/ml, with 46 having greater than 50% inhibition.
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New diarylheptanoids from the rhizomes of Dioscorea spongiosa and their antiosteoporotic activity
Jun Yin,Kyoji Kouda,Yasuhiro Tezuka,Quan Le Tran,Tatsuro Miyahara,Yingjie Chen,Shigetoshi Kadota +6 more
TL;DR: The isolated compounds, except for diospongin A, exerted potent inhibitory activities on bone resorption induced by parathyroid hormone in a bone organ culture system.
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In vitro antiplasmodial activity of antimalarial medicinal plants used in Vietnamese traditional medicine
Quan Le Tran,Yasuhiro Tezuka,Jun-ya Ueda,Nhan Trung Nguyen,Yukiko Maruyama,Khurshida Begum,Hye Sook Kim,Yusuke Wataya,Qui Kim Tran,Shigetoshi Kadota +9 more
TL;DR: Among 42 extracts, prepared from 14 medicinal plants used in Vietnamese traditional medicine to treat malaria, 24 were found to have antiplasmodial activity by inhibiting the growth of the chloroquine-resistant Plasmodium falciparum strain FCR-3 with EC(50) values less than 10 microg/ml.
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Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity.
TL;DR: Majonoside R(2) (3), the main saponin in Vietnamese ginseng, showed strong protective activity against D-GalN/TNF-alpha-induced cell death in primary cultured mouse hepatocytes, demonstrating that the hepatocytoprotective effect of Vietnamese gINSeng is due to dammarane-type triterpene saponins that have an ocotillol-type side chain, a characteristic constituent of Vietnameseginseng.