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Quirine A. ten Bosch
Researcher at Wageningen University and Research Centre
Publications - 32
Citations - 1065
Quirine A. ten Bosch is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 11, co-authored 24 publications receiving 756 citations. Previous affiliations of Quirine A. ten Bosch include Centre national de la recherche scientifique & University of Notre Dame.
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Journal ArticleDOI
Biased efficacy estimates in phase-III dengue vaccine trials due to heterogeneous exposure and differential detectability of primary infections across trial arms.
Guido España,Cosmina Hogea,Adrienne Guignard,Quirine A. ten Bosch,Amy C. Morrison,David L. Smith,Thomas W. Scott,Alexander C. Schmidt,T. Alex Perkins +8 more
TL;DR: Simulation models of vaccine trials that account for heterogeneity in dengue virus transmission and vaccine trial protocols can be used to anticipate the extent of bias in field trials and to aid in their interpretation.
Journal ArticleDOI
Contributions from the silent majority dominate dengue virus transmission
Quirine A. ten Bosch,Hannah E. Clapham,Louis Lambrechts,Louis Lambrechts,Veasna Duong,Philippe Buchy,Philippe Buchy,Benjamin M. Althouse,Benjamin M. Althouse,Alun L. Lloyd,Lance A. Waller,Amy C. Morrison,Uriel Kitron,Gonzalo M. Vazquez-Prokopec,Thomas W. Scott,T. Alex Perkins +15 more
TL;DR: The need to reorient current practices for outbreak response to adoption of pre-emptive strategies that account for contributions of undetected infections in surveillance programs, when assessing intervention impact, and when modeling mosquito-borne virus transmission is emphasized.
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Epidemiological characteristics of an urban plague epidemic in Madagascar, August–November, 2017: an outbreak report
Rindra Randremanana,Voahangy Andrianaivoarimanana,Birgit Nikolay,Beza Ramasindrazana,Juliette Paireau,Quirine A. ten Bosch,Jean Marius Rakotondramanga,Soloandry Rahajandraibe,Soanandrasana Rahelinirina,Fanjasoa Rakotomanana,Feno Manitra Jacob Rakotoarimanana,Lea Randriamampionona,Vaoary Razafimbia,Mamy Jean de Dieu Randria,Mihaja Raberahona,Guillain Mikaty,Anne Sophie Le Guern,Lamina Arthur Rakotonjanabelo,Charlotte Faty Ndiaye,Voahangy Rasolofo,Eric Bertherat,Maherisoa Ratsitorahina,Simon Cauchemez,Laurence Baril,André Spiegel,Minoarisoa Rajerison +25 more
TL;DR: This predominantly urban plague epidemic was characterised by a large number of notifications in two major urban areas and an unusually high proportion of pneumonic forms, with only 23% having one or more positive laboratory tests.
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Implementation and applications of EMOD, an individual-based multi-disease modeling platform
Anna Bershteyn,Jaline Gerardin,Daniel Bridenbecker,Christopher W. Lorton,Jonathan Bloedow,Robert S Baker,Guillaume Chabot-Couture,Ye Chen,Thomas Fischle,Kurt Frey,Jillian S. Gauld,Hao Hu,Amanda S Izzo,Daniel J. Klein,Dejan Lukacevic,Kevin A. McCarthy,Joel C. Miller,André Lin Ouédraogo,T. Alex Perkins,Jeffrey Steinkraus,Quirine A. ten Bosch,Quirine A. ten Bosch,Hung-Fu Ting,Svetlana Titova,Bradley G. Wagner,Philip A. Welkhoff,Edward Allen Wenger,Christian N Wiswell +27 more
TL;DR: The process and advantages of a multi-disease framework approach developed with formal software support is described and the levels of detail, flexible configurability and modularity enabled by EMOD are described.
Journal ArticleDOI
Lovastatin induces neuroprotection through tumor necrosis factor receptor 2 signaling pathways.
Amalia M. Dolga,Ingrid M. Nijholt,Anghelus Ostroveanu,Quirine A. ten Bosch,Paul G.M. Luiten,Ulrich L. M. Eisel +5 more
TL;DR: It is found that lovastatin protects cortical neurons in a concentration-dependent manner against glutamate-mediated excitotoxicity and via activation of TNF-R2-signaling pathways.