R
R. Gomez
Researcher at Seoul National University
Publications - 38
Citations - 2357
R. Gomez is an academic researcher from Seoul National University. The author has contributed to research in topics: Amniotic fluid & Premature rupture of membranes. The author has an hindex of 25, co-authored 38 publications receiving 2202 citations. Previous affiliations of R. Gomez include Ben-Gurion University of the Negev.
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Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection.
TL;DR: Spontaneous human parturition was associated with a significant increase in amniotic fluid concentrations of MMP-8 in both term and preterm gestation, and patients with preterm labor who delivered preterm had a significantly higher median amniotics fluid M MP-8 concentration.
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Antimicrobial peptides in amniotic fluid: defensins, calprotectin and bacterial/permeability-increasing protein in patients with microbial invasion of the amniotic cavity, intra-amniotic inflammation, preterm labor and premature rupture of membranes.
Jimmy Espinoza,Tinnakorn Chaiworapongsa,R. Romero,Samuel Edwin,C. Rathnasabapathy,R. Gomez,Emmanuel Bujold,Natalia Camacho,Yeon Mee Kim,Sonia S. Hassan,Sean C. Blackwell,Janice E. Whitty,Susan Berman,Mark Redman,B. H. Yoon,Yoram Sorokin +15 more
TL;DR: Elevated amniotic fluid concentrations of BPI, immunoreactive HNP 1-3, BPI and calprotectin are associated with intra-amniotic inflammation, histological chorioamnionitis and shorter amniocentesis-to-delivery interval in patients presenting with preterm labor with intact membranes.
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Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection.
Eli Maymon,Roberto Romero,Percy Pacora,Maria-Teresa Gervasi,R. Gomez,Samuel S. Edwin,Bo Hyun Yoon +6 more
TL;DR: The authors' observations provide evidence for a novel regulation of gelatinolytic activity in vivo and explore the participation of these enzymes in labor, rupture of membranes, and microbial invasion of the amniotic cavity.
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The tumor necrosis factor α and its soluble receptor profile in term and preterm parturition
TL;DR: Observations provide support for the thesis that preterm parturition is a pathologic condition and increased tumor necrosis factor α soluble receptor concentrations may attenuate the deleterious effects of the excess of tumor necrot factor α found in pathologic labor.
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Neutrophil elastase and secretory leukocyte protease inhibitor in prelabor rupture of membranes, parturition and intra-amniotic infection.
B. R. Helmig,R. Romero,Jimmy Espinoza,Tinnakorn Chaiworapongsa,Emmanuel Bujold,R. Gomez,Kjell Ohlsson,Niels Uldbjerg +7 more
TL;DR: Neutrophil elastase (NE), a multifunctional serine protease stored in azurophilic granules of mature neutrophils, is capable of intracellular degradation of proteins during phagocytosis and extracellular degrade of connective tissue during an inflammatory process.