S
Sonia S. Hassan
Researcher at Wayne State University
Publications - 430
Citations - 29333
Sonia S. Hassan is an academic researcher from Wayne State University. The author has contributed to research in topics: Pregnancy & Amniotic fluid. The author has an hindex of 79, co-authored 426 publications receiving 25138 citations. Previous affiliations of Sonia S. Hassan include University of Ulsan & National Institutes of Health.
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Journal ArticleDOI
The preterm parturition syndrome
Roberto Romero,Jimmy Espinoza,Juan Pedro Kusanovic,Francesca Gotsch,Sonia S. Hassan,Offer Erez,Tinnakorn Chaiworapongsa,Moshe Mazor +7 more
TL;DR: The evidence indicating that the pathological processes implicated in the preterm parturition syndrome include: intrauterine infection/inflammation; uterine ischaemia; (3) uterine overdistension; (4) abnormal allograft reaction; (5) allergy; (6) cervical insufficiency; and (7) hormonal disorders (progesterone related and corticotrophin‐releasing factor related).
Journal ArticleDOI
A novel signaling pathway impact analysis
Adi L. Tarca,Sorin Draghici,Purvesh Khatri,Sonia S. Hassan,Pooja Mittal,Jung-Sun Kim,Chong Jai Kim,Juan Pedro Kusanovic,Roberto Romero +8 more
TL;DR: A novel signaling pathway impact analysis (SPIA) that combines the evidence obtained from the classical enrichment analysis with a novel type of evidence, which measures the actual perturbation on a given pathway under a given condition.
Journal ArticleDOI
The role of inflammation and infection in preterm birth.
Roberto Romero,Jimmy Espinoza,Jimmy Espinoza,Luís F. Gonçalves,Luís F. Gonçalves,Juan Pedro Kusanovic,Lara A. Friel,Sonia S. Hassan,Sonia S. Hassan +8 more
TL;DR: The role of inflammation in preterm and term parturition is reviewed, which is the only pathological process for which both a firm causal link with preterm birth and a molecular pathophysiology defined are established.
Journal ArticleDOI
Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial
Sonia S. Hassan,Sonia S. Hassan,Roberto Romero,Roberto Romero,Roberto Romero,D. Vidyadhari,S. Fusey,Jason K. Baxter,Meena Khandelwal,J. Vijayaraghavan,Y. Trivedi,Priya Soma-Pillay,P. Sambarey,Ashlesha K. Dayal,V. Potapov,John M. O'Brien,John M. O'Brien,V. Astakhov,O. Yuzko,W. Kinzler,B. Dattel,H. Sehdev,L. Mazheika,D. Manchulenko,M. T. Gervasi,Lisa M. Sullivan,Agustin Conde-Agudelo,James A. Phillips,George W. Creasy +28 more
TL;DR: The efficacy and safety of using micronized vaginal progesterone gel to reduce the risk of preterm birth and associated neonatal complications in women with a sonographic short cervix is determined.
Journal ArticleDOI
The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women
Roberto Romero,Roberto Romero,Roberto Romero,Sonia S. Hassan,Sonia S. Hassan,Pawel Gajer,Adi L. Tarca,Douglas Fadrosh,Lorraine Nikita,Marisa Galuppi,Marisa Galuppi,Ronald F. Lamont,Ronald F. Lamont,Piya Chaemsaithong,Jezid Miranda,Tinnakorn Chaiworapongsa,Tinnakorn Chaiworapongsa,Jacques Ravel +17 more
TL;DR: Differences in the composition and stability of the microbial community between pregnant and non-pregnant women were observed and can serve as the basis to study the relationship between the vaginal microbiome and adverse pregnancy outcomes.