R
R.L. Goodacre
Researcher at McMaster University
Publications - 14
Citations - 1864
R.L. Goodacre is an academic researcher from McMaster University. The author has contributed to research in topics: Inflammatory bowel disease & Mast cell. The author has an hindex of 12, co-authored 14 publications receiving 1774 citations.
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Journal ArticleDOI
A New Measure of Health Status for Clinical Trials in Inflammatory Bowel Disease
Gordon H. Guyatt,Alba Mitchell,E. Jan Irvine,Joel Singer,Nancy Williams,R.L. Goodacre,Cathy Tompkins +6 more
TL;DR: The Inflammatory Bowel Disease Questionnaire shows promise as a measure of health status for clinical trials in IBD, and responsiveness appeared greater in patients with ulcerative colitis than in those with Crohn's disease.
Journal ArticleDOI
Quality of life in patients with inflammatory bowel disease.
Alba Mitchell,Gordon H. Guyatt,Joel Singer,E. Irvine,R.L. Goodacre,Cathy Tompkins,Nancy Williams,Fred Wagner +7 more
TL;DR: It is concluded that despite troublesome intestinal and systemic symptoms, most patients with IBD avoid major disruption in work and personal lives and Physicians must inquire specifically about emotional problems relating to IBD.
Journal Article
Small bowel and colonic permeability to 51Cr-EDTA in patients with active inflammatory bowel disease.
TL;DR: The rectal test differentiated small bowel disease from colonic disease with an accuracy of 85%.
Journal Article
Reversibility of increased intestinal permeability to 51Cr-EDTA in patients with gastrointestinal inflammatory diseases.
R T Jenkins,D B Jones,R.L. Goodacre,Stephen M. Collins,G Coates,Richard H. Hunt,John Bienenstock +6 more
TL;DR: Investigation of intestinal permeability in adults with inflammatory gastrointestinal diseases found increased 24-h urinary excretion of 51Cr-EDTA had a high association with intestinal inflammation, and test specificity and sensitivity were 96% and 57%, respectively.
Journal Article
14C-urea breath test for the detection of Helicobacter pylori.
S Veldhuyzen van Zanten,K. M. A. J. Tytgat,J. Hollingsworth,S. Jalali,F.A. Rshid,Barry Bowen,J. Goldie,R.L. Goodacre,Robert H. Riddell,Richard H. Hunt +9 more
TL;DR: The 14C-urea breath test is a better "gold standard" for the detection of Helicobacter pylori than histology and/or culture and correlated with histological improvement in gastritis.