R
R. Phillip Dellinger
Researcher at University of Medicine and Dentistry of New Jersey
Publications - 31
Citations - 1881
R. Phillip Dellinger is an academic researcher from University of Medicine and Dentistry of New Jersey. The author has contributed to research in topics: Intensive care & Sepsis. The author has an hindex of 14, co-authored 31 publications receiving 1768 citations. Previous affiliations of R. Phillip Dellinger include University of Chicago & Cooper University Hospital.
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Journal ArticleDOI
Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: Relationship to hemodynamics, oxygen transport, and survival
Stephen Trzeciak,R. Phillip Dellinger,Joseph E. Parrillo,Massimiliano Guglielmi,Jasmeet Bajaj,Nicole L. Abate,Ryan C. Arnold,Susan Colilla,Sergio Zanotti,Steven M. Hollenberg +9 more
TL;DR: Early microcirculatory perfusion indices in severe sepsis and septic shock are more markedly impaired in nonsurvivors compared with survivors and with increasing severity of global cardiovascular dysfunction.
Journal ArticleDOI
Cardiovascular management of septic shock.
TL;DR: This review will cover septic shock as a manifestation of severe sepsis, the collision of the body’s defenses with the invading organism, and based on current understanding of the pathophysiology, this seems to be particularly appropriate terminology.
Journal ArticleDOI
Diagnostic and Prognostic Implications of Endotoxemia in Critical Illness: Results of the MEDIC Study
John C. Marshall,Debra Foster,Jean Louis Vincent,Deborah J. Cook,Jonathan Cohen,R. Phillip Dellinger,Steven M. Opal,Edward Abraham,Stephen J. Brett,Terry Smith,Sangeeta Mehta,Anastasia Derzko +11 more
TL;DR: Stepwise logistic regression analysis showed that elevated Acute Physiology and Chronic Health Evaluation II score, gram-negative infection, and emergency admission status were independent predictors of EA.
Journal ArticleDOI
Regional distribution of acoustic-based lung vibration as a function of mechanical ventilation mode
R. Phillip Dellinger,Smith Jean,Ismail Cinel,Christina Tay,Susmita Rajanala,Yael A. Glickman,Joseph E. Parrillo +6 more
TL;DR: Better patient synchronization with the ventilator, greater downward movement of the diaphragm, and decelerating flow waveform are potential physiologic explanations for the redistribution of vibration energy to lower lung regions in pressure-targeted modes of mechanical ventilation.
Journal ArticleDOI
Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: Results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial
R. Phillip Dellinger,John F. Tomayko,Derek C. Angus,Steven M. Opal,Michael A. Cupo,Sharon McDermott,Annie Ducher,Thierry Calandra,Jonathan Cohen +8 more
TL;DR: Treatment with phospholipid emulsion did not reduce 28-day all-cause mortality, or reduce the onset of new organ failure in patients with suspected or confirmed Gram-negative severe sepsis.