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Ismail Cinel

Researcher at Marmara University

Publications -  126
Citations -  3461

Ismail Cinel is an academic researcher from Marmara University. The author has contributed to research in topics: Sepsis & Lung injury. The author has an hindex of 29, co-authored 120 publications receiving 2972 citations. Previous affiliations of Ismail Cinel include Gazi University & Cooper University Hospital.

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Molecular biology of inflammation and sepsis: a primer.

TL;DR: The identification of the toll-like receptors and the associated concept of innate immunity based upon pathogen- or damage-associated molecular pattern molecules allowed significant advances in the understanding of the pathophysiology of sepsis.
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Liver and kidney toxicity in chronic use of opioids: An experimental long term treatment model

TL;DR: The findings pointed out the risk of increased lipid peroxidation, hepatic and renal damage due to long term use of opioids, especially morphine, which should be kept in mind during chronic usage.
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Resuscitating the Microcirculation in Sepsis: The Central Role of Nitric Oxide, Emerging Concepts for Novel Therapies, and Challenges for Clinical Trials

TL;DR: This Bench-to-Bedside review focuses on the central role and vital importance of the nitric oxide molecule in maintaining microcirculatory homeostasis and patency, especially when the microcirculation sustains an insult (as with sepsis).
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Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 15-18 March 2016

Ryon M. Bateman, +1875 more
- 20 Apr 2016 - 
TL;DR: This research presents a novel probabilistic procedure called “spot-spot analysis” that allows for real-time analysis of the response of the immune system to natural disasters.
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The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model.

TL;DR: The chronic use of NAC inhibited MPO activity and lipid peroxidation, which resulted in reduction of apoptosis in lung in this CLP model, and lung histopathology was also protected by NAC in CLP-induced sepsis.