R
R. Schimke
Researcher at University of Kansas
Publications - 1
Citations - 611
R. Schimke is an academic researcher from University of Kansas. The author has contributed to research in topics: Renal cell carcinoma & Von Hippel–Lindau disease. The author has an hindex of 1, co-authored 1 publications receiving 589 citations.
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Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma
Bernd R. Seizinger,Guy A. Rouleau,Laurie J. Ozelius,A.H. Lane,G. E. Farmer,J M Lamiell,Jonathan Haines,J. W M Yuen,D. Collins,Danielle Majoor-Krakauer,Tom I. Bonner,Christopher G. Mathew,Allan E. Rubenstein,John J. Halperin,Allyn McConkie-Rosell,Jane Green,James A. Trofatter,Bruce A.J. Ponder,L. Eierman,M. I. Bowmer,R. Schimke,Ben A. Oostra,Neil Aronin,David I. Smith,Harry A. Drabkin,M. H. Waziri,Wendy Hobbs,Robert L. Martuza,P. M. Conneally,Y. E. Hsia,James F. Gusella +30 more
TL;DR: The VHL gene is linked to the locus encoding the human homologoue of the RAF1 oncogene, which maps to chromosome 3p25 (ref. 4), which suggests that the defect responsible for the VHL phenotype is not a mutation in the RAF 1 gene itself.