R
R. Scott Turner
Researcher at Georgetown University
Publications - 85
Citations - 5649
R. Scott Turner is an academic researcher from Georgetown University. The author has contributed to research in topics: Medicine & Dementia. The author has an hindex of 34, co-authored 67 publications receiving 4891 citations. Previous affiliations of R. Scott Turner include University of California, San Diego & University of Pennsylvania.
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Journal ArticleDOI
FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease
Norman L. Foster,Judith L. Heidebrink,Christopher M. Clark,William J. Jagust,Steven E. Arnold,Nancy R. Barbas,Charles DeCarli,R. Scott Turner,Robert A. Koeppe,Roger Higdon,Satoshi Minoshima +10 more
TL;DR: Visual interpretation of FDG-PET after brief training is more reliable and accurate in distinguishing FTD from AD than clinical methods alone and adds important information that appropriately increases diagnostic confidence, even among experienced dementia specialists.
Journal ArticleDOI
A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
R. Scott Turner,Ronald G. Thomas,Suzanne Craft,Christopher H. van Dyck,Jacobo Mintzer,Brigid Reynolds,James B. Brewer,Robert A. Rissman,Rema Raman,Paul S. Aisen +9 more
TL;DR: This study provides Class II evidence that for patients with AD resveratrol is safe, well-tolerated, and alters some AD biomarker trajectories.
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Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.
Charbel Moussa,Michaeline Hebron,Xu Huang,Jaeil Ahn,Robert A. Rissman,Paul S. Aisen,R. Scott Turner +6 more
TL;DR: Data suggest that resveratrol decreases CSF MMP9, modulates neuro-inflammation, and induces adaptive immunity, and SIRT1 activation may be a viable target for treatment or prevention of neurodegenerative disorders.
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In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease
William C. Kreisl,Chul Hyoung Lyoo,Meghan McGwier,Joseph Snow,Kimberly J. Jenko,Nobuyo Kimura,Winston Corona,Cheryl L. Morse,Sami S. Zoghbi,Victor W. Pike,Francis J. McMahon,R. Scott Turner,Robert B. Innis +12 more
TL;DR: The results suggest that neuroinflammation, indicated by increased (11)C-PBR28 binding to TSPO, occurs after conversion of mild cognitive impairment to Alzheimer's disease and worsens with disease progression.
Journal ArticleDOI
ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo
Sonya B. Dumanis,Joseph A. Tesoriero,Lenard W. Babus,Madeline T. Nguyen,Justin H. Trotter,Mary Jo LaDu,Edwin J. Weeber,R. Scott Turner,Baoji Xu,G. William Rebeck,Hyang Sook Hoe +10 more
TL;DR: It is demonstrated that apoE isoforms differentially affect dendritic complexity and spine formation, suggesting a role for APOE genotypes not only in acute and chronic brain injuries including AD, but also in normal brain functions.