Rachel A. F. Wozniak

TL;DR: This Review compares and contrasts the core functions for some of the well-studied ICEs and discusses them in the broader context of mobile-element and genome evolution.

TL;DR: A plasmid-based system to capture and isolate SXT/R391 ICEs for sequencing is developed and analyses suggest that there may be a network of phylogenetic relationships among sequences found in all types of mobile genetic elements.

TL;DR: Two genes within SXT are identified, now designated mosA and mosT (for maintenance of SXT Antitoxin and Toxin), that promote SXT stability; expression of mosT greatly impaired cell growth and mosA expression ameliorated MosT toxicity.

TL;DR: In this paper, the authors carried out genomic and functional analyses of an SXT-related ICE derived from a Spanish isolate of Photobacterium damselae subsp. piscicida, the causative agent of fish pasteurellosis.

TL;DR: The development of a polymyxin B-trimethoprim (PT) ophthalmic formulation containing the antibiotic rifampin which exhibits synergistic antimicrobial activity toward a panel of contemporary ocular clinical S. aureus and P. aeruginosa isolates, low spontaneous resistance frequency, and in vitro bactericidal kinetics and antibiofilm activities equaling or exceeding the antimicrobial properties of moxifloxacin is described.