R
Rachela Popovtzer
Researcher at Bar-Ilan University
Publications - 119
Citations - 5521
Rachela Popovtzer is an academic researcher from Bar-Ilan University. The author has contributed to research in topics: Cancer & Colloidal gold. The author has an hindex of 36, co-authored 108 publications receiving 4118 citations. Previous affiliations of Rachela Popovtzer include Tel Aviv University & University of Michigan.
Papers
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Journal ArticleDOI
Targeted gold nanoparticles enable molecular CT imaging of cancer.
Rachela Popovtzer,Ashish Agrawal,Nicholas A. Kotov,Aron Popovtzer,James M. Balter,Thomas E. Carey,Raoul Kopelman +6 more
TL;DR: A targeted molecular imaging platform that enables, for the first time, cancer detection at the cellular and molecular level with standard clinical CT, based on gold nanoprobes that selectively and sensitively target tumor selective antigens while inducing distinct contrast in CT imaging.
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Ultrasmall Oxygen-Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy.
Fei Gong,Liang Cheng,Nailin Yang,Oshra Betzer,Liangzhu Feng,Qiang Zhou,Yonggang Li,Ruihua Chen,Rachela Popovtzer,Zhuang Liu +9 more
TL;DR: A new type of sono‐sensitizing agent with high SDT efficacy, multimodal imaging functions, and rapid clearance is presented, an agent which is promising for noninvasive SDT cancer treatment.
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Targeted gold nanoparticles enable molecular CT imaging of cancer: an in vivo study.
TL;DR: In vivo the feasibility of cancer diagnosis based on molecular markers rather than on anatomical structures is demonstrated, using clinical computed tomography, and it is shown that active tumor targeting is more efficient and specific than passive targeting.
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In Vivo Neuroimaging of Exosomes Using Gold Nanoparticles
Oshra Betzer,Nisim Perets,Ariel Angel,Menachem Motiei,Tamar Sadan,Gal Yadid,Daniel Offen,Rachela Popovtzer +7 more
TL;DR: This method for noninvasive in vivo neuroimaging and tracking of exosomes, based on glucose-coated gold nanoparticle (GNP) labeling and computed tomography imaging, can serve as a powerful diagnostic tool for various brain disorders and could potentially enhance exosome-based treatments for neuronal recovery.
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Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury.
Shaowei Guo,Shaowei Guo,Nisim Perets,Oshra Betzer,Shahar Ben-Shaul,Anton Sheinin,Izhak Michaelevski,Rachela Popovtzer,Daniel Offen,Shulamit Levenberg +9 more
TL;DR: It is demonstrated that when given intranasally, exosomes derived from mesenchymal stem cells could pass the blood brain barrier, and migrate to the injured spinal cord area, and MSC-Exo loaded with phosphatase and tensin homolog small interfering RNA (ExoPTEN) could attenuate the expression of PTEN in thejured spinal cord region followingintranasal administrations.