Rafael Silva-Rocha

TL;DR: It is argued that adoption of the SEVA format can become a shortcut to fill the phenomenal gap between the existing power of DNA synthesis and the actual engineering of predictable and efficacious bacteria.

TL;DR: This review addresses the distinct role of network architecture and biochemical/kinetic parameters in the materialization of various archetypical robust gene expression circuits in prokaryotes.

TL;DR: New players in cellulose degradation such as accessory proteins with non-catalytic functions secreted in different carbon sources, transporters, transcription factors, and CAZymes, that specifically respond in response to either cellulose or sophorose are revealed.

TL;DR: An overview of new findings in the gene expression regulation network of T. reesei is presented and how synthetic biology strategies can be used to create engineered promoters to efficiently synthesize enzymes for biomass degradation to produce bioethanol is presented.

TL;DR: It is argued that designing new functions with biological parts requires the recognition of logic gates not yet assigned but surely present in the meta‐genome, the orthogonalization and disambiguation of natural regulatory modules and the development of ways to tackle the connectivity and the definition of boundaries between minimal biological components.