Showing papers by "Rahul N. Khurana published in 2007"
TL;DR: Optical coherence tomography provides consistent pachymetry mapping, whereas Orbscan II significantly underestimates corneal thickness in the presence of central cornea scars.
94 citations
TL;DR: The results indicate that the three- dimensional stereoscopic camera-based viewing system may be a novel viewing system in ophthalmic surgery with improved ergonomics with respect to traditional microscopic viewing.
18 citations
TL;DR: Two recent cases of fungal endophthalmitis in crack users who similarly disclose dissolving crack-cocaine in lemon juice injection are reported.
Abstract: The Centers for Disease Control and Prevention recently reported that a substantial number of drug misusers in the US are injecting crack-cocaine instead of smoking it,1 owing to the decreased availability and increased cost of powdered cocaine. The use of lemon juice to dissolve crack-cocaine has been shown to cause abscesses, permanent vein damage and infections.2 Furthermore, heroin dissolved in preserved lemon juice was documented to be a source of Candida albicans in multiple, small epidemics of fungal endophthalmitis in the 1980s in the UK and Australia.3,4 We report here two recent cases of fungal endophthalmitis in crack users who similarly disclose dissolving crack-cocaine in lemon juice injection.
A 34-year-old male intravenous drug user presented to his primary care physician with high fever …
18 citations
TL;DR: Vogt–Koyanagi–Harada disease should be included in differential diagnosis of bilateral optic neuritis, even when extraocular manifestations of the disease are absent, and fluorescein angiography of the retina led to the diagnosis of VKH disease in all patients.
Abstract: Vogt-Koyanagi-Harada (VKH) disease is a granulomatous multisystem inflammatory disorder that classically affects the uvea, inner ear, meninges, and skin. We report three patients who presented with initial findings suggestive of bilateral optic neuritis requiring CSF analysis and brain images. None of these patients had extraocular changes. Fluorescein angiography of the retina led to the diagnosis of VKH disease in all patients. Vogt-Koyanagi-Harada disease should be included in differential diagnosis of bilateral optic neuritis, even when extraocular manifestations of the disease are absent. In such cases, fluorescein angiography will aid diagnosis.
17 citations
TL;DR: The use of oxygenated solutions appears to affect ERG readings after pars plana vitrectomy, and rabbits treated with BSS-plus + O2 exhibited a statistically significantly earlier return of ERG voltage to baseline values compared with both BSS and BSS + L.
Abstract: PURPOSE: To investigate the effect of oxygenated intraocular irrigating solutions on electroretinograms (ERGs) for postvitrectomy rabbits. METHODS: Eight groups of five rabbits each underwent pars plana vitrectomy on the right eye; the left eye of each rabbit served as control. The intraocular irrigating solutions were balanced salt solution (BSS), BSS-plus, BSS + oxygen (BSS + O2), BSS-plus + O2, and combinations of each with the addition of endoillumination (L). All animals were evaluated by single-flash scotopic electroretinography on the operated and nonoperated eyes before surgery and at 1 hour, 1 day, 1 week, and 1 month after surgery by an unmasked observer. The main outcome measures were dark-adapted b-wave amplitudes of operated eye/nonoperated eye ratios. The results for the different groups were compared by analysis of variance. RESULTS: Mean dark-adapted b-wave amplitudes of operated eye/nonoperated eye ratios +/- SD for BSS-plus and BSS-plus + O2 before surgery and 1 hour, 1 day, 1 week, and 1 month after surgery were 1.01 +/- 0.09, 0.50 +/- 0.11, 0.95 +/- 0.11, 0.97 +/- 0.11, and 0.99 +/- 0.08 and 0.98 +/- 0.08, 0.59 +/- 0.10, 0.92 +/- 0.06, 0.97 +/- 0.08, and 0.97 +/- 0.10, respectively. At both 1 hour and 1 day after surgery, rabbits treated with BSS-plus + O2 had an earlier b-wave return to baseline findings, but the differences were not statistically significant (P > 0.05). Mean dark-adapted b-wave amplitudes of operated eye/nonoperated eye ratios +/- SD for BSS and BSS + O2 before surgery and 1 hour, 1 day, 1 week, and 1 month after surgery were 1.02 +/- 0.10, 0.47 +/- 0.09, 0.77 +/- 0.07, 0.89 +/- 0.07, and 0.89 +/- 0.07 and 1.02 +/- 0.06, 0.62 +/- 0.16, 0.94 +/- 0.09, 0.97 +/- 0.08, and 0.96 +/- 0.06, respectively. One hour and 1 day after surgery, ERG readings for rabbits treated with BSS + O2 exhibited a statistically significantly earlier return of ERG voltage to baseline values compared with both BSS and BSS + L (P = 0.05 and P = 0.02, respectively). One day after surgery, rabbits treated with BSS alone had the lowest ERG ratios. One week and 1 month after surgery, for all solutions tested other than BSS, ERG values were within normal limits. CONCLUSION: The use of oxygenated solutions appears to affect ERG readings after pars plana vitrectomy. Further studies to evaluate the role of oxygenated solutions in different vitreoretinal surgical procedures are warranted.
11 citations
TL;DR: The in-line oxygenator is an efficient tool for oxygenating BSS and LR solution and represents a potential efficient and convenient method to oxygenate irrigating solutions for vitreoretinal surgeries.
Abstract: Purpose:We describe a novel method to oxygenate intraocular irrigation solutions involving an in-line oxygenator.Methods:Either lactated Ringer (LR) solution or balanced salt solution (BSS) was oxygenated with the FE390 Stainless In-line Oxygenation Assembly (Beer, Beer, and More Beer, Concord, CA).
5 citations
TL;DR: A 76-YEAR-old WHITE man with an unremarkable medical history was seen with a 5-month history of floaters and painless loss of vision and found to have primary cutaneous melanoma on his back with multiple metastases to the brain and died 6 months later.
Abstract: A 76-YEAR-OLD WHITE man with an unremarkable medical history was seen with a 5-month history of floaters and painless loss of vision. Best-corrected visual acuity was 20/100 OD and 20/25 OS. Slitlamp examination of the right eye was remarkable for pigmented cells in the anterior chamber and vitreous. Funduscopy of the right eye revealed preretinal pigmentation in the posterior pole that tracked along the vascular arcades and in the periphery (Figure 1). Fluorescein angiography showed blockage secondary to the pigment deposits (Figure 2). The left eye was unremarkable. The patient underwent excision of the pigmented epiretinal membrane over the macula through pars plana. Postoperatively, the patient’s visual acuity did not improve. Histologically, the specimen showed pigmented epithelioid and spindle melanoma cells (Figure 3). The patient was subsequently found to have primary cutaneous melanoma on his back with multiple metastases to the brain. The patient declined treatment and died 6 months later.
5 citations
TL;DR: A bulbar conjunctival keloid confirmed by immunohistochemical analysis and scanning electron microscopy is described, which is thought to be the result of altered wound healing with excessive scar tissue formation.
Abstract: Keloids are usually formed in individuals after skin trauma and are thought to be the result of altered wound healing with excessive scar tissue formation.1 We describe a bulbar conjunctival keloid confirmed by immunohistochemical analysis and scanning electron microscopy.
A 48-year-old Hispanic man presented with a medial conjunctival lesion in his left eye. The patient had underwent pterygium surgery in the same location 2 years previously. At 6 months after surgery, he noted progressive growth of a conjunctival mass that persisted over the next year. On examination, his vision was 20/25 in the right eye and 20/30 in the left …
4 citations