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Raina M. Lourens

Researcher at Armed Forces Institute of Pathology

Publications -  6
Citations -  1630

Raina M. Lourens is an academic researcher from Armed Forces Institute of Pathology. The author has contributed to research in topics: Influenza A virus & Influenza A virus subtype H5N1. The author has an hindex of 6, co-authored 6 publications receiving 1546 citations. Previous affiliations of Raina M. Lourens include Roy J. and Lucille A. Carver College of Medicine.

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Characterization of the 1918 influenza virus polymerase genes

Jeffery K. Taubenberger, +7 more
- 06 Oct 2005 - 
TL;DR: In this article, the authors present sequence and phylogenetic analyses of the complete genome of the 1918 influenza virus and propose that the 1918 virus was not a reassortant virus (like those of the 1957 and 1968 pandemics), but more likely an entirely avian-like virus that adapted to humans.
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Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore

Teri J. Franks, +11 more
- 01 Aug 2003 - 
TL;DR: Postmortem lung sections from 8 patients who died from SARS during the spring 2003 Singapore outbreak studied, finding the predominant pattern of lung injury in all 8 cases was diffuse alveolar damage, and the histology varied according to the duration of illness.
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1918 influenza pandemic caused by highly conserved viruses with two receptor-binding variants.

Ann H. Reid, +7 more
- 01 Oct 2003 - 
TL;DR: The results suggest that in the early stages of an influenza A pandemic, mutations that occur during replication do not become fixed so that a uniform “consensus” strain circulates for some time.
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Novel Origin of the 1918 Pandemic Influenza Virus Nucleoprotein Gene

Ann H. Reid, +4 more
- 15 Nov 2004 - 
TL;DR: The results are consistent with the existence of a currently unknown host for influenza, with an NP similar to current avian strain NPs at the amino acid level but with many synonymous nucleotide differences, suggesting evolutionary isolation from the currently characterized avian influenza virus gene pool.
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Molecular virology: Was the 1918 pandemic caused by a bird flu? Was the 1918 flu avian in origin? (Reply)

Jeffery K. Taubenberger, +7 more
- 27 Apr 2006 - 
TL;DR: It is proposed that the virus responsible for the 1918 human influenza pandemic was avian-like, which to us is a reasonable interpretation of all the available data from phylogenetic, sequence, serological and historical analysis, combined with what is known of influenza A virus biology.