Rais V. Pavlov

TL;DR: Different combinations of cyclodextrin platform conjugated with polymers is considered as drug delivery systems with synergetic effect that improves solubility, targeting and biocompatibility of formulations.

TL;DR: Hydroxyethyl bearing gemini surfactants were used to augment phosphatidylcholine based liposomes to achieve higher stability and enhanced cellular uptake and penetration, and liposomal 2-PAM was found to reactivate 27% of brain acetylcholinesterase, which is, to the authors' knowledge, the first example of such high degree of reactivation after intravenous administration ofliposomal drug.

TL;DR: A review of the use of lipid systems to deliver active substances to the human body is presented in this paper, where various lipid compositions modified with amphiphilic open-chain and macrocyclic compounds, peptide molecules and alternative target ligands are discussed.

TL;DR: It is demonstrated how the positively charged targeting moieties can be exploited to achieve outstanding mitochondria colocalization with a comparative study of n-tetradecyltriphenylphosphonium bromide and 1-(2-hydroxyethyl)-3- tetradecyl-1H-imidazol-3-ium b romide modified liposomes.

TL;DR: In this paper, a homologous series of isothiuronium surfactants (S-alkylisothionium bromides, CnSU, where n = 10, 12, 14, 16, 18, 18) are described and aggregation properties are comprehensively characterized by a variety of techniques.