R
Rajendra Bhadane
Researcher at Åbo Akademi University
Publications - 15
Citations - 250
Rajendra Bhadane is an academic researcher from Åbo Akademi University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 7 publications receiving 97 citations. Previous affiliations of Rajendra Bhadane include Rajiv Gandhi Proudyogiki Vishwavidyalaya & Gyanvihar University.
Papers
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Journal ArticleDOI
Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development
Outi M. H. Salo-Ahen,Ida Alanko,Rajendra Bhadane,Alexandre M. J. J. Bonvin,Rodrigo V. Honorato,Shakhawath Hossain,André H. Juffer,Aleksei Kabedev,Maija Lahtela-Kakkonen,Anders S. Larsen,Eveline Lescrinier,Parthiban Marimuthu,Muhammad Usman Mirza,Ghulam Mustafa,Ariane Nunes-Alves,Ariane Nunes-Alves,Tatu Pantsar,Tatu Pantsar,Atefeh Saadabadi,Kalaimathy Singaravelu,Michiel Vanmeert +20 more
TL;DR: A broad overview of the current application possibilities of MD in drug discovery and pharmaceutical development is given, including how MD can be used in studying the crystalline and amorphous solids, the stability ofAmorphous drug or drug-polymer formulations, and drug solubility.
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Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CL pro .
Mubarak A. Alamri,Muhammad Tahir ul Qamar,Muhammad Usman Mirza,Rajendra Bhadane,Safar M. Alqahtani,Iqra Muneer,Matheus Froeyen,Outi M. H. Salo-Ahen +7 more
TL;DR: The identified FDA-approved anti-hepatitis-C virus drugs paritaprevir and simeprevir could be ready for clinical trials to treat infected patients and help curb COVID-19.
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Simultaneous estimation of tramadol hydrochloride, paracetamol and domperidone by rp-hplc in tablet formulation
TL;DR: In this article, a high performance liquid chromatography method was developed and validated for the quantitation of tramadol, paracetamol, and domperidone in pharmaceutical formulations.
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Stability-Indicating Assay Method for Estimation of Olmesartan Medoxomil and its Metabolite
TL;DR: In this paper, a novel stability indicating high performance liquid chromatographic assay method was developed and validated for Olmesartan medoxomil and its degradant product.
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Design, Synthesis, in vitro and in silico Characterization of 2‐Quinolone‐L‐alaninate‐1,2,3‐triazoles as Antimicrobial Agents
Oussama Moussaoui,Rajendra Bhadane,Riham Sghyar,Janez Ilaš,El Mestafa El Hadrami,S. Chakroune,Outi M. H. Salo-Ahen +6 more
TL;DR: Inspired by the broad antibacterial activities of various heterocyclic compounds such as 2‐quinolone derivatives, new methyl‐(2‐oxo‐1,2‐dihydroquinolin‐4‐yl)‐L‐alaninate‐ 1,2,3‐triazole derivatives are designed and synthesized via 1,3-dipolar cycloaddition reaction of 1‐propargyl‐2‐quinoleone‐L-alaninate with