R
Rajendra Prasad Nagarajan
Researcher at Annamalai University
Publications - 9
Citations - 210
Rajendra Prasad Nagarajan is an academic researcher from Annamalai University. The author has contributed to research in topics: DNA damage & Oxidative stress. The author has an hindex of 7, co-authored 9 publications receiving 137 citations.
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Journal ArticleDOI
Linalool prevents oxidative stress activated protein kinases in single UVB-exposed human skin cells
Srithar Gunaseelan,Agilan Balupillai,Kanimozhi Govindasamy,Kanimozhi Govindasamy,Karthikeyan Ramasamy,Ganesan Muthusamy,Mohana Shanmugam,Radhiga Thangaiyan,Beaulah Mary Robert,Rajendra Prasad Nagarajan,Veeramani kandan Ponniresan,Pierson Rathinaraj +11 more
TL;DR: The present findings substantiate that linalool may act as a photoprotective agent against UVB-induced skin damages and modulates MAPK and NF-κB signaling in HDFa cells.
Journal ArticleDOI
Caffeic acid prevents UVB radiation induced photocarcinogenesis through regulation of PTEN signaling in human dermal fibroblasts and mouse skin
Agilan Balupillai,Rajendra Prasad Nagarajan,Karthikeyan Ramasamy,Kanimozhi Govindasamy,Ganesan Muthusamy +4 more
TL;DR: The present results confirm that CA significantly inhibits single UVB‐induced CPDs formation, oxidative DNA damage, ROS generation and frequency of apoptotic cell death in human dermal fibroblasts (HDFa).
Journal ArticleDOI
Ultraviolet radiation-induced carcinogenesis: Mechanisms and experimental models
Karthikeyan Ramasamy,Mohana Shanmugam,Agilan Balupillai,Kanimozhi Govindhasamy,Srithar Gunaseelan,Ganesan Muthusamy,Beualah Mary Robert,Rajendra Prasad Nagarajan +7 more
TL;DR: The current progress in the study on ultraviolet B (UVB)-mediated carcinogenesis is discussed and appropriate experimental models for both ultraviolet A- and UVB- mediated carcinogenesis are outlined.
Journal ArticleDOI
Inhibitory Effect of Ursolic Acid on Ultraviolet B Radiation-Induced Oxidative Stress and Proinflammatory Response-Mediated Senescence in Human Skin Dermal Fibroblasts.
Ramachandran Samivel,Rajendra Prasad Nagarajan,Umadevi Subramanian,Adnan A. Khan,Ali M Masmali,Turki M Almubrad,Saeed Akhtar +6 more
TL;DR: Results revealed that UA has the potential to mitigate UVB-induced extracellular damage by interfering with the ROS-mediated apoptotic induction and photoaging senescence and thus is a potential therapeutic agent to protect the skin againstUVB-irradiation induced photooxidative damage.
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Naringin prevents ultraviolet-B radiation-induced oxidative damage and inflammation through activation of peroxisome proliferator-activated receptor γ in mouse embryonic fibroblast (NIH-3T3) cells.
TL;DR: Naringin prevents UVB‐mediated inflammation and oxidative damage in NIH‐3T3 cells probably over controlling NF‐κB expression and activation of PPARγ.