R
Ramji K. Bhandari
Researcher at University of North Carolina at Greensboro
Publications - 63
Citations - 2289
Ramji K. Bhandari is an academic researcher from University of North Carolina at Greensboro. The author has contributed to research in topics: Sex change & Honeycomb grouper. The author has an hindex of 26, co-authored 52 publications receiving 1908 citations. Previous affiliations of Ramji K. Bhandari include University of Missouri & University of the Ryukyus.
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Journal ArticleDOI
Effects of the environmental estrogenic contaminants bisphenol A and 17α-ethinyl estradiol on sexual development and adult behaviors in aquatic wildlife species
Ramji K. Bhandari,Sharon L. Deem,Dawn K. Holliday,Caitlin M. Jandegian,Christopher D. Kassotis,Susan C. Nagel,Donald E. Tillitt,Frederick S. vom Saal,Cheryl S. Rosenfeld +8 more
TL;DR: How diverse epigenetic changes might be a unifying mechanism of how BPA and EE2 disrupt several processes across species is considered, as these effects have been the best characterized across taxa.
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Environmentally Induced Transgenerational Epigenetic Reprogramming of Primordial Germ Cells and the Subsequent Germ Line
Michael K. Skinner,Carlos Guerrero Bosagna M Haque,Eric E. Nilsson,Ramji K. Bhandari,John R. McCarrey +4 more
TL;DR: Interestingly, disruptions in DNA methylation patterns and altered transcriptomes were distinct between germ cells at the onset of gonadal sex determination at embryonic day 13 (E13) and after cord formation in the testis at embryonicday 16 (E16).
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Gonadal Restructuring and Correlative Steroid Hormone Profiles during Natural Sex Change in Protogynous Honeycomb Grouper (Epinephelus merra)
TL;DR: The present results suggest that low serum E2 levels and degeneration of oocytes accompanied by concomitant increase in the 11-KT levels and proliferation of spermatogenic germ cells are probably the events mediating protogynous sex change in the honeycomb grouper.
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Transgenerational effects from early developmental exposures to bisphenol A or 17α-ethinylestradiol in medaka, Oryzias latipes
TL;DR: The present observations suggest that BPA or EE2 exposure during development induces transgenerational phenotypes of reproductive impairment and compromised embryonic survival in fish of subsequent generations, which may have negative impacts on populations of fish inhabiting contaminated aquatic environments.
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The role estrogens play in sex differentiation and sex changes of fish
TL;DR: The results strongly suggest that endogenous estrogen acts as an ovarian inducer, and that the lack of steroid hormone including androgen is important for testicular differentiation.