D
Donald E. Tillitt
Researcher at United States Geological Survey
Publications - 157
Citations - 7781
Donald E. Tillitt is an academic researcher from United States Geological Survey. The author has contributed to research in topics: Thiaminase & Micropterus. The author has an hindex of 48, co-authored 148 publications receiving 7283 citations. Previous affiliations of Donald E. Tillitt include University of Missouri.
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Journal ArticleDOI
Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure.
TL;DR: This review compiles and evaluates existing scientific information on the use, limitations, and procedural considerations for EROD activity (a catalytic measurement of cytochrome P4501A induction) as a biomarker in fish.
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Overview of a workshop on screening methods for detecting potential (anti‐) estrogenic/androgenic chemicals in wildlife
Gerald T. Ankley,Ellen Mihaich,Ralph G. Stahl,Donald E. Tillitt,Theo Colborn,Suzzanne McMaster,Ron Miller,John A. Bantle,Pamela M. Campbell,Nancy D. Denslow,Richard L. Dickerson,Leroy C. Folmar,Michael Fry,John P. Giesy,L. Earl Gray,Patrick D. Guiney,Thomas H. Hutchinson,Sean W. Kennedy,Vincent J. Kramer,Gerald A. LeBlanc,M. A. Mayes,Alison Nimrod,Reynaldo Patiño,Richard E. Peterson,Richard Purdy,Robert K. Ringer,Peter Thomas,Les Touart,Glen Van Der Kraak,Timothy R. Zacharewski +29 more
TL;DR: Existing methods suitable for identifying chemicals with these mechanisms of action in reptiles and amphibians are limited, but in the future, tests with species from these classes may prove highly effective as screens.
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Toxicogenomics in regulatory ecotoxicology.
Gerald T. Ankley,George P. Daston,Sigmund J. Degitz,Nancy D. Denslow,Robert A. Hoke,Sean W. Kennedy,Ann L. Miracle,Edward J. Perkins,Jason Snape,Donald E. Tillitt,Charles R. Tyler,Donald J. Versteeg +11 more
TL;DR: Roles of toxicogenomics in the field of regulatory ecotoxicology are considered, current limitations in the science and practice of genomics are explored, and possible avenues to approach and resolve some of the major challenges are proposed.
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Characterization of the H4IIE rat hepatoma cell bioassay as a tool for assessing toxic potency of planar halogenated hydrocarbons in environmental samples
TL;DR: An in vitro bioassay of cytochrome P450IA1 catalytic activity in the H4IIE cells in response to planar halogenated hydrocarbons (PHHs) was repeatable over time and standards were reproducible among laboratories when dosing conditions were similar.
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Effects of the environmental estrogenic contaminants bisphenol A and 17α-ethinyl estradiol on sexual development and adult behaviors in aquatic wildlife species
Ramji K. Bhandari,Sharon L. Deem,Dawn K. Holliday,Caitlin M. Jandegian,Christopher D. Kassotis,Susan C. Nagel,Donald E. Tillitt,Frederick S. vom Saal,Cheryl S. Rosenfeld +8 more
TL;DR: How diverse epigenetic changes might be a unifying mechanism of how BPA and EE2 disrupt several processes across species is considered, as these effects have been the best characterized across taxa.