J
John R. McCarrey
Researcher at University of Texas at San Antonio
Publications - 148
Citations - 10911
John R. McCarrey is an academic researcher from University of Texas at San Antonio. The author has contributed to research in topics: Gene & Somatic cell. The author has an hindex of 52, co-authored 141 publications receiving 10088 citations. Previous affiliations of John R. McCarrey include Johns Hopkins University & Beckman Research Institute.
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An abundance of X-linked genes expressed in spermatogonia
P. Jeremy Wang,P. Jeremy Wang,John R. McCarrey,Fang Yang,Fang Yang,David C. Page,David C. Page +6 more
TL;DR: The findings indicate that the X chromosome has a predominant role in pre-meiotic stages of mammalian spermatogenesis, and hypothesize that theX chromosome acquired this prominent role in male germ-cell development as it evolved from an ordinary, unspecialized autosome.
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Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.
Tal Kafri,Mira Ariel,Michael Brandeis,Ruth Shemer,Lance E. Urven,John R. McCarrey,Howard Cedar,Aharon Razin +7 more
TL;DR: The results form a basis for the understanding of the biochemical mechanisms and role of DNA methylation in embryonic development.
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The Murine Testicular Transcriptome: Characterizing Gene Expression in the Testis During the Progression of Spermatogenesis
TL;DR: A developmental testis gene expression time course profiling the expression patterns of ∼36 000 transcripts on the Affymetrix MGU74v2 GeneChip platform at 11 distinct time points was created to gain a greater understanding of the molecular changes necessary for and elicited by the development of the testis.
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Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene
TL;DR: It is unexpected to find that the intronless autosomal PGK sequence reported here is not a pseudogene, but is rather a functional gene that has retained a complete open reading frame, and is actively expressed in mammalian spermatogenesis.
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The H19 methylation imprint is erased and re‐established differentially on the parental alleles during male germ cell development
TL;DR: It is shown here that both parental alleles are devoid of methylation in male and female mid-gestation embryonic germ cells, suggesting that methylation imprints are erased in the germ cells prior to this time.