Ramon Correa

TL;DR: It is hypothesized that radiomic texture descriptors can capture tumor heterogeneity manifested as a result of molecular variations in tumor hypoxia, on routine treatment naïve MRI, and these imaging based texture surrogate markers of Hypoxia can discriminate GBM patients as short-term (STS), mid- term (MTS), and long-term survivors (LTS).

TL;DR: The preliminary results suggest that 3D shape attributes from the lesion habitat can differentially express across pseudoprogression and tumor progression and could be used to distinguish these radiographically similar pathologies.

TL;DR: The findings suggest that prognostic radiomic features from routine Gd-T1w MRI may also be significantly associated with key biological processes that affect response to chemotherapy in GBM.

TL;DR: This work addresses two critical challenges with regard to developing robust radiomic approaches: the lack of availability of reliable segmentation labels for GBM tumor sub-compartments, and identifying "reproducible" radiomic features that are robust to segmentation variability across readers/sites.

TL;DR: Preliminary findings demonstrated significant associations of prognostic radiomic features with disease-specific histologic attributes in glioblastoma, with implications for risk-stratifying patients with GBM for personalized treatment decisions.