R
Randall D. Learish
Researcher at University of Wisconsin-Madison
Publications - 2
Citations - 1133
Randall D. Learish is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Transplantation & Embryonic stem cell. The author has an hindex of 2, co-authored 2 publications receiving 1123 citations. Previous affiliations of Randall D. Learish include Promega.
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Journal ArticleDOI
Embryonic Stem Cell-Derived Glial Precursors: A Source of Myelinating Transplants
Oliver Brüstle,Kimberly N. Jones,Kimberly N. Jones,Randall D. Learish,Khalad Karram,Khalid Choudhary,Khalid Choudhary,Otmar D. Wiestler,Ian D. Duncan,Ronald D.G. McKay +9 more
TL;DR: Transplantation in a rat model of a human myelin disease shows that ES cell-derived precursors interact with host neurons and efficiently myelinate axons in brain and spinal cord.
Journal ArticleDOI
Intraventricular transplantation of oligodendrocyte progenitors into a fetal myelin mutant results in widespread formation of myelin.
TL;DR: Data suggest that myelin repair might be achieved by intraventricular delivery and transependymal incorporation of myelin‐producing cells, and similar ex vivo manipulation with genes known to promote survival, migration, or proliferation of the transplanted cells could be used to enhance repair.