R
Rannnik J. Xavier
Researcher at Harvard University
Publications - 1
Citations - 334
Rannnik J. Xavier is an academic researcher from Harvard University. The author has contributed to research in topics: Innate immune system & Acquired immune system. The author has an hindex of 1, co-authored 1 publications receiving 240 citations.
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BCG-induced trained immunity in NK cells: role for non-specific protection to infection
Johanneke Kleinnijenhuis,Jessica Quintin,Frank Preijers,Leo A. B. Joosten,Cor Jacobs,Rannnik J. Xavier,Jos W. M. van der Meer,Reinout van Crevel,Mihai G. Netea +8 more
TL;DR: BCG vaccination of healthy volunteers increased proinflammatory cytokine production following ex vivo stimulation of NK cells with mycobacteria and other unrelated pathogens up until at least three months after vaccination, which suggests that NK cells may contribute to the non-specific (heterologous) beneficial effects of BCG vaccination.