R
Raphael K. Sung
Researcher at University of California, San Francisco
Publications - 18
Citations - 1064
Raphael K. Sung is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Tachycardia & Gene. The author has an hindex of 10, co-authored 18 publications receiving 1007 citations. Previous affiliations of Raphael K. Sung include Stanford University & University of Pennsylvania.
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Journal ArticleDOI
The role of selection in the evolution of human mitochondrial genomes.
Toomas Kivisild,Peidong Shen,Dennis P. Wall,Bao H. Do,Raphael K. Sung,Karen Davis,Giuseppe Passarino,Peter A. Underhill,Curt Scharfe,Antonio Torroni,Rosaria Scozzari,David Modiano,Alfredo Coppa,Peter de Knijff,Marcus W. Feldman,Luigi Luca Cavalli-Sforza,Peter J. Oefner +16 more
TL;DR: The surplus of nonsynonymous mutations is a general feature of the young branches of the phylogenetic tree, affecting also those that are found only in Africa, and a new calibration method is introduced to estimate the coalescent times of mtDNA haplogroups.
Journal ArticleDOI
Population genetic implications from sequence variation in four Y chromosome genes.
Peidong Shen,Frank Wang,Peter A. Underhill,Claudia Franco,Wei-Hsien Yang,Adriane Roxas,Raphael K. Sung,Alice A. Lin,Richard W. Hyman,Douglas Vollrath,Ronald W. Davis,Luigi Luca Cavalli-Sforza,Peter J. Oefner +12 more
TL;DR: Analysis of the frequencies of derived alleles for all four genes showed that they more closely fit the expectation of a Luria-Delbrück distribution than a distribution expected under a constant population size model, providing evidence for exponential population growth.
Journal Article
Conservation of the class I beta-tubulin gene in human populations and lack of mutations in lung cancers and paclitaxel-resistant ovarian cancers.
Sanja Sale,Raphael K. Sung,Peidong Shen,Kristine M. Yu,Yan Wang,George E. Duran,Jong-Hyeok Kim,Tito Fojo,Peter J. Oefner,Branimir I. Sikic +9 more
TL;DR: The data demonstrate a very high degree of sequence conservation in class I tubulin, suggesting that all residues are important in tubulin structure and function.
Journal ArticleDOI
beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer
Perry S. Mongroo,Cameron N. Johnstone,Izabela Naruszewicz,Chungyee Leung-Hagesteijn,Raphael K. Sung,Leanne Carnio,Anil K. Rustgi,Gregory E. Hannigan +7 more
TL;DR: The results suggest that loss of ParvB expression is a novel mechanism for upregulating ILK activity in tumors and functional studies of the effects of ParVB on ILK signaling are facilitated.
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Long-term electrical survival analysis of Riata and Riata ST silicone leads: National Veterans Affairs experience.
Raphael K. Sung,Barry M. Massie,Barry M. Massie,Paul D. Varosy,Hans Moore,John S. Rumsfeld,Byron K. Lee,Edmund C. Keung,Edmund C. Keung +8 more
TL;DR: It is suggested that large-scale remote monitoring may be an effective tool for continued implantable cardioverter-defibrillator system surveillance in patients with Riata/ST leads in order to prevent inappropriate shocks or failed device interventions.