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Wei-Hsien Yang
Researcher at Stanford University
Publications - 4
Citations - 1452
Wei-Hsien Yang is an academic researcher from Stanford University. The author has contributed to research in topics: Population & Genetic marker. The author has an hindex of 4, co-authored 4 publications receiving 1429 citations.
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Journal ArticleDOI
Y chromosome sequence variation and the history of human populations
Peter A. Underhill,Peidong Shen,A. A. Lin,Li Jin,Giuseppe Passarino,Wei-Hsien Yang,Kauffman E,Batsheva Bonne-Tamir,Jaume Bertranpetit,Paolo Francalacci,Muntaser E. Ibrahim,Trefor Jenkins,Kidd,S.Q. Mehdi,Mark Seielstad,R. S. Wells,Alberto Piazza,Ronald W. Davis,Marcus W. Feldman,Luigi Luca Cavalli-Sforza,Peter J. Oefner +20 more
TL;DR: Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of the authors' species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history.
Journal ArticleDOI
Genome-wide mapping with biallelic markers in Arabidopsis thaliana
Raymond J. Cho,Michael N. Mindrinos,Michael N. Mindrinos,Daniel R. Richards,R J Sapolsky,M Anderson,Eliana Drenkard,Julia Dewdney,T L Reuber,M Stammers,Nancy A. Federspiel,Athanasios Theologis,Wei-Hsien Yang,Earl Hubbell,M Au,E Y Chung,Deval A. Lashkari,Bertrand Lemieux,Caroline Dean,Robert J. Lipshutz,Frederick M. Ausubel,Ronald W. Davis,Peter J. Oefner +22 more
TL;DR: The construction of a biallelic genetic map in A. thaliana with a resolution of 3.5 cM is reported and its use in mapping Eds16, a gene involved in the defence response to the fungal pathogen Erysiphe orontii is mapped.
Journal ArticleDOI
Population genetic implications from sequence variation in four Y chromosome genes.
Peidong Shen,Frank Wang,Peter A. Underhill,Claudia Franco,Wei-Hsien Yang,Adriane Roxas,Raphael K. Sung,Alice A. Lin,Richard W. Hyman,Douglas Vollrath,Ronald W. Davis,Luigi Luca Cavalli-Sforza,Peter J. Oefner +12 more
TL;DR: Analysis of the frequencies of derived alleles for all four genes showed that they more closely fit the expectation of a Luria-Delbrück distribution than a distribution expected under a constant population size model, providing evidence for exponential population growth.
Journal ArticleDOI
Population genetic implications from DNA polymorphism in random human genomic sequences.
Peidong Shen,Molly Buchholz,Raphael K. Sung,Adriane Roxas,Claudia Franco,Wei-Hsien Yang,Raja Jagadeesan,Karen Davis,Peter J. Oefner +8 more
TL;DR: The discrepancy in Tajima's D statistic between 22 autosomal genes and random STSs suggests that, in the absence of significant mutation rate heterogeneity, the more negative values for genes are a consequence of directional selection rather than population growth.