R
Raul Moreno
Researcher at Complutense University of Madrid
Publications - 231
Citations - 6073
Raul Moreno is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Myocardial infarction & Stent. The author has an hindex of 35, co-authored 231 publications receiving 5301 citations. Previous affiliations of Raul Moreno include European Atomic Energy Community & Hospital General Universitario Gregorio Marañón.
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Journal ArticleDOI
Platelet Function Profiles in Patients With Type 2 Diabetes and Coronary Artery Disease on Combined Aspirin and Clopidogrel Treatment
Dominick J. Angiolillo,Antonio Fernández-Ortiz,Esther Bernardo,Celia Ramírez,Manel Sabaté,Pilar Jiménez-Quevedo,Rosana Hernández,Raul Moreno,Javier Escaned,Fernando Alfonso,Camino Bañuelos,Marco A. Costa,Theodore A. Bass,Carlos Macaya +13 more
TL;DR: Diabetic patients have increased platelet reactivity compared with nondiabetic subjects on combined aspirin and clopidogrel treatment and reduced sensitivity to antiplatelet drugs may contribute to the increased atherothombotic risk in diabetic patients.
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Randomized Trial of Primary PCI with or without Routine Manual Thrombectomy
Sanjit S. Jolly,S. Yusuf,Brandi Meeks,J. Pogue,S. Kedev,Lehana Thabane,Goran Stankovic,Raul Moreno,Anthony H. Gershlick,S. Chowdhary,Shahar Lavi,K. Niemelä,Ivo Bernat,Y. Xu,Alvaro Avezum,Ravinay Bhindi,Samir Pancholy,Peggy Gao,Petr Widimsky +18 more
TL;DR: In patients with STEMI who were undergoing primary PCI, routine manual thrombectomy, as compared with PCI alone, did not reduce the risk of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure within 180 days but was associated with an increased rate of stroke within 30 days.
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Randomized Comparison of Sirolimus-Eluting Stent Versus Standard Stent for Percutaneous Coronary Revascularization in Diabetic Patients The Diabetes and Sirolimus-Eluting Stent (DIABETES) Trial
Manel Sabaté,Pilar Jiménez-Quevedo,Dominick J. Angiolillo,Joan Antoni Gómez-Hospital,Fernando Alfonso,Rosana Hernández-Antolín,Javier Goicolea,Camino Bañuelos,Javier Escaned,Raul Moreno,Cristina Fernández,Francisco Fernández-Avilés,Carlos Macaya +12 more
TL;DR: This multicenter, randomized trial demonstrated that sirolimus stent implantation is safe and efficacious in reducing both angiographic and clinical parameters of restenosis compared with standard stents in diabetic patients with de novo coronary stenoses.
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High clopidogrel loading dose during coronary stenting: effects on drug response and interindividual variability
Dominick J. Angiolillo,Antonio Fernández-Ortiz,Esther Bernardo,Celia Ramírez,Manel Sabaté,Camino Bañuelos,Rosana Hernández-Antolín,Javier Escaned,Raul Moreno,Fernando Alfonso,Carlos Macaya +10 more
TL;DR: The use of a 600 mg clopidogrel LD in patients undergoing coronary stenting optimises platelet inhibitory effects early after intervention and may provide a more effective protection against early thrombotic complications.
Journal ArticleDOI
Contribution of Gene Sequence Variations of the Hepatic Cytochrome P450 3A4 Enzyme to Variability in Individual Responsiveness to Clopidogrel
Dominick J. Angiolillo,Antonio Fernández-Ortiz,Esther Bernardo,Celia Ramírez,Ugo Cavallari,Elisabetta Trabetti,Manel Sabaté,Rosana Hernández,Raul Moreno,Javier Escaned,Fernando Alfonso,Camino Bañuelos,Marco A. Costa,Theodore A. Bass,Pier Franco Pignatti,Carlos Macaya +15 more
TL;DR: The IVS10+12G>A polymorphism of the CYP3A4 gene modulates platelet activation in patients treated with clopidogrel and may therefore contribute to clopIDogrel response variability.