Ravindra K. Pandey

TL;DR: In preliminary in vivo studies, ketobacteriochlorins were found to be more photodynamically active than the related vic-dihydroxy analogues and replacement of the methyl ester functionalities with di-tert-butylaspartic acids enhanced the in vivo efficacy.

TL;DR: The pyropheophorbide compounds are injected into a host and accumulate in tumor tissue to a higher degree than surrounding normal tissues as discussed by the authors, and they absorb light further in the red, optimizing tissue penetration.

TL;DR: Spectrosopic studies suggest that conformations similar to those determined by X-ray crystallography are present in solution for the 5,15-dialkyl- and 5, 15-diaryl-substituted porphyrins.

TL;DR: In this paper, a series of symmetrical and unsymmetrical bisporphyrins, bischlorins, and biscorroles, and of porphyrin−chlorin and porphrin−corrole dyads possessing ethylene, phenyl, and stilbene linking units are described.

TL;DR: The pyropheophorbide compounds have been shown to have a variety of characteristics when used in photodynamic therapy as mentioned in this paper, and these characteristics are further improved when the compounds are bound to a target specific component such as a ligand capable of binding to a specific cellular receptor (e.g. growth hormones and growth factors) or an antibody capable of Binding to a particular antigen.