R
Raynald Bergeron
Researcher at Université de Montréal
Publications - 41
Citations - 4942
Raynald Bergeron is an academic researcher from Université de Montréal. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 23, co-authored 39 publications receiving 4743 citations. Previous affiliations of Raynald Bergeron include Yale University & Merck & Co..
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Journal ArticleDOI
Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle *
Chunli Yu,Yan Chen,Gary W. Cline,Dongyan Zhang,Haihong Zong,Yanlin Wang,Raynald Bergeron,Jason K. Kim,Samuel W. Cushman,Gregory J. Cooney,Bronwyn Atcheson,Morris F. White,Edward W. Kraegen,Gerald I. Shulman +13 more
TL;DR: The hypothesis that an increase in plasma fatty acid concentration results in a increase in intracellular fatty acyl-CoA and DAG concentrations, which results in activation of PKC-θ leading to increased IRS-1 Ser307 phosphorylation is supported.
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Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR
TL;DR: It is concluded that AMPK activation increases cardiac muscle glucose uptake through translocation of GLUT-4 via a pathway that is independent of PI3K.
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Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis.
Raynald Bergeron,Jian Ming Ren,Kevin S. Cadman,Irene K. Moore,Pascale Perret,Marc Pypaert,Lawrence H. Young,Clay F. Semenkovich,Gerald I. Shulman +8 more
TL;DR: Chronic phosphocreatine depletion during beta-GPA supplementation led to the activation of muscle AMPK that was associated with increased NRF-1 binding activity, increased cytochrome c content, and increased muscle mitochondrial density.
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Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.
Raynald Bergeron,Stephen F. Previs,Gary W. Cline,Pascale Perret,Raymond R. Russell,Lawrence H. Young,Gerald I. Shulman +6 more
TL;DR: In this article, the effects of AMP activation on skeletal muscle glucose transport activity and whole-body carbohydrate and lipid metabolism in an insulin-resistant rat model were examined in the obese Zucker rats.
Journal ArticleDOI
Effect of AMPK activation on muscle glucose metabolism in conscious rats
Raynald Bergeron,Raymond R. Russell,Lawrence H. Young,Jian-Ming Ren,Melissa Marcucci,Agnes Lee,Gerald I. Shulman +6 more
TL;DR: The activation of AMPK by AICAR increases skeletal muscle glucose transport activity both in vivo and in vitro, and this cellular pathway may play an important role in exercise-induced increase in glucose Transport activity.