R
Rebecca Gardner
Researcher at Seattle Children's
Publications - 99
Citations - 7984
Rebecca Gardner is an academic researcher from Seattle Children's. The author has contributed to research in topics: Medicine & Chimeric antigen receptor. The author has an hindex of 23, co-authored 69 publications receiving 5367 citations. Previous affiliations of Rebecca Gardner include University of Washington & Seattle Children's Research Institute.
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Journal ArticleDOI
Chimeric Antigen Receptor T Cells for B-Cell Acute Lymphoblastic Leukemia.
Francesco Ceppi,Rebecca Gardner +1 more
TL;DR: This review covers the development of CAR T cells for B-ALL, citing the remarkable efficacy of inducing remissions in a very high-risk population of patients and the identification of targets beyond CD19.
Journal ArticleDOI
Anakinra utilization in refractory pediatric CAR T-cell associated toxicities
Caroline Diorio,Anant Vatsayan,Aimee C Talleur,Colleen Annesley,Jennifer Jaroscak,Haneen Shalabi,Amanda K. Ombrello,Michelle Hudspeth,Shannon L. Maude,Rebecca Gardner,Nirali N. Shah +10 more
TL;DR: This research presents a novel, scalable, scalable and scalable approach that aims to improve the quality of life of children undergoing bone Marrow Transplantation and Cellular Therapy in the United States.
Journal ArticleDOI
Clinical Experience of CAR T Cell Immunotherapy for Relapsed and Refractory Infant ALL Demonstrates Feasibility and Favorable Responses
Colleen Annesley,Colleen Annesley,Corinne Summers,Corinne Summers,Corinne Summers,Michael A. Pulsipher,Alan S. Wayne,Julie Rivers,Julie Rivers,Adam J. Lamble,Adam J. Lamble,Ashley Wilson,Qian Vicky Wu,Adam Brand,Stephanie Mgebroff,Christopher Brown,Catherine Lindgren,Julie R. Park,Julie R. Park,Michael C. Jensen,Michael C. Jensen,Rebecca Gardner +21 more
TL;DR: The experience using CAR T cell immunotherapy for patients with R/R infant ALL enrolled on clinical trials PLAT-02 andPLAT-05 is reported, with results indicating small patient size, heavily pre-treated disease and high leukemia burden are often characteristics of this subgroup of patients that pose unique challenges to apheresis and manufacture of a T cell product.
Journal ArticleDOI
Is intrachromosomal amplification of chromosome 21 (iAMP21) always intrachromosomal
TL;DR: A case of iAMP21 that does not fit the formal FISH definition is presented, demonstrating that CMA is helpful for the detection of this entity when FISH results are ambiguous and showing that RUNX1 is not the primary target of amplification.
Journal ArticleDOI
Humoral immunogenicity of the seasonal influenza vaccine before and after CAR-T-cell therapy: a prospective observational study.
Carla S Walti,Andrea N. Loes,Andrea N. Loes,Kiel Shuey,Elizabeth M Krantz,Jim Boonyaratanakornkit,Jim Boonyaratanakornkit,Jacob Keane-Candib,Tillie Loeffelholz,Caitlin R Wolf,Justin J. Taylor,Rebecca Gardner,Rebecca Gardner,Damian J. Green,Damian J. Green,Andrew J. Cowan,Andrew J. Cowan,David G. Maloney,David G. Maloney,Cameron J. Turtle,Cameron J. Turtle,Steven A. Pergam,Steven A. Pergam,Helen Y. Chu,Jesse D. Bloom,Jesse D. Bloom,Joshua A. Hill,Joshua A. Hill +27 more
TL;DR: This paper conducted a prospective observational study of the humoral immunogenicity of commercially available 2019-2020 inactivated influenza vaccines in adults immediately prior to or while in durable remission after CAR-T-cell therapy, as well as controls.