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Rebecca M. Teasdale
Researcher at University of Iowa
Publications - 7
Citations - 3882
Rebecca M. Teasdale is an academic researcher from University of Iowa. The author has contributed to research in topics: Growth factor & Basic fibroblast growth factor. The author has an hindex of 7, co-authored 7 publications receiving 3795 citations. Previous affiliations of Rebecca M. Teasdale include University of Iowa Hospitals and Clinics.
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Journal ArticleDOI
Cpg motifs in bacterial dna trigger direct b-cell activation
Arthur M. Krieg,Ae-Kyung Yi,Sara Matson,Thomas J. Waldschmidt,Gail A. Bishop,Gail A. Bishop,Rebecca M. Teasdale,Gary A. Koretzky,Dennis M. Klinman +8 more
TL;DR: The potent immune activation by CpG oligon nucleotides has impli-cations for the design and interpretation of studies using 'antisense' oligonucleotides and points to possible new applications as adjuvants.
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Oligonucleotides with novel, cationic backbone substituents: aminoethylphosphonates.
Reza Fathi,Qing Huang,George Coppola,William Delaney,Rebecca M. Teasdale,Arthur M. Krieg,Alan F. Cook +6 more
TL;DR: (2-Aminoethyl)phosphonates represent a novel approach to the introduction of positive charges into the backbone of oligonucleotides that formed a more stable duplex with DNA or RNA than its corresponding natural counterpart.
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Activation of protein kinase-C differentially regulates insulin-like growth factor-I and basic fibroblast growth factor messenger RNA levels.
William L. Lowe,Mark A. Yorek,Charles W. Karpen,Rebecca M. Teasdale,John G. Hovis,Brian N. Albrecht,Carmelita Prokopiou +6 more
TL;DR: Rat dermal fibroblasts in culture were used as a model system to assess the effect of activation of protein kinase-C on the levels of the mRNAs encoding IGF-I and another growth factor, basic fibroblast growth factor (bFGF).
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Characterization of a rat insulin-like growth factor I gene promoter.
TL;DR: It is shown that the 5'-flanking region of exon 1 is capable of regulating transcription of IGF-I mRNAs and the relative use of different start sites was different from start site usage by the endogenous gene.
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Inhibition of T4 polynucleotide kinase activity by phosphorothioate and chimeric oligodeoxynucleotides.
TL;DR: Four different chimeric phosphorodithioate ODN showed markedly different potencies of inhibition, suggesting that inhibition of PNK activity can be sequence specific.