R
Reed Pifer
Researcher at University of Texas Health Science Center at Houston
Publications - 2
Citations - 21
Reed Pifer is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Carbapenem-resistant enterobacteriaceae & Ertapenem. The author has an hindex of 2, co-authored 2 publications receiving 6 citations.
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Journal ArticleDOI
IS26-mediated amplification of blaOXA-1 and blaCTX-M-15 with concurrent outer membrane porin disruption associated with de novo carbapenem resistance in a recurrent bacteraemia cohort
William C Shropshire,Samuel L. Aitken,Samuel L. Aitken,Reed Pifer,Jiwoong Kim,Micah M. Bhatti,Xiqi Li,Awdhesh Kalia,Jessica Galloway-Peña,Jessica Galloway-Peña,Pranoti Sahasrabhojane,Cesar A. Arias,David E. Greenberg,David E. Greenberg,Blake Hanson,Samuel A. Shelburne,Samuel A. Shelburne +16 more
TL;DR: These data demonstrate IS26-mediated mechanisms underlying β-lactamase gene amplification with concurrent outer membrane porin disruption driving emergence of clinical non-CP-CRE, a cohort of ESBL-E bacteraemia cases in Houston, TX, USA.
Posted ContentDOI
Β-lactamase Amplification and Porin Loss Drive Progressive β-lactam Resistance in Recurrent ESBL Enterobacteriaceae Bacteremia
William C Shropshire,Samuel L. Aitken,Samuel L. Aitken,Reed Pifer,Jiwoong Kim,Micah M. Bhatti,Xiqi Li,Awdhesh Kalia,Jessica Galloway-Peña,Jessica Galloway-Peña,Pranoti Sahasrabhojane,Cesar A. Arias,Cesar A. Arias,David E. Greenberg,David E. Greenberg,Blake Hanson,Samuel A. Shelburne,Samuel A. Shelburne +17 more
TL;DR: In this paper, the authors investigated 16 longitudinal, recurrent cases of extended spectrum B-lactamase (ESBL)-positive Enterobacteriaceae bacteremia to gain insights into mechanisms underlying the emergence of non-carbapenemase producing CRE (non-CP-CRE) using a combination of short- and long-read sequencing technologies.