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David E. Greenberg
Researcher at University of Texas Southwestern Medical Center
Publications - 80
Citations - 2597
David E. Greenberg is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Pseudomonas aeruginosa & Granulibacter bethesdensis. The author has an hindex of 25, co-authored 72 publications receiving 2117 citations. Previous affiliations of David E. Greenberg include University of Texas Health Science Center at Houston & National Institutes of Health.
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Journal ArticleDOI
Pulmonary Nontuberculous Mycobacterial Disease: Prospective Study of a Distinct Preexisting Syndrome
Richard D. Kim,David E. Greenberg,Mary Ehrmantraut,Shireen V. Guide,Li Ding,Yvonne R. Shea,Margaret R. Brown,Milica S. Chernick,Wendy K. Steagall,Connie G. Glasgow,JingPing Lin,Clara Jolley,Lynn Sorbara,Mark Raffeld,Suvimol Hill,Nilo A. Avila,Vandana Sachdev,Lisa A. Barnhart,Victoria L. Anderson,Reginald J. Claypool,Dianne Hilligoss,Mary Garofalo,Alan Fitzgerald,Sandra Anaya-O'Brien,Dirk Darnell,Rosamma DeCastro,Heather M. Menning,Stacy M. Ricklefs,Stephen F. Porcella,Kenneth N. Olivier,Joel Moss,Steven M. Holland +31 more
TL;DR: Patients with PNTM infection are taller and leaner than control subjects, with high rates of scoliosis, pectus excavatum, mitral valve prolapse, and cystic fibrosis transmembrane conductance regulator mutations, but without recognized immune defects.
Journal ArticleDOI
Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis
Elizabeth P. Sampaio,Elizabeth P. Sampaio,Amy P. Hsu,Joseph Pechacek,Hannelore I. Bax,Hannelore I. Bax,Dalton L. Dias,Michelle L. Paulson,Prabha Chandrasekaran,Lindsey B. Rosen,Daniel Serra de Carvalho,Daniel Serra de Carvalho,Li Ding,Donald C. Vinh,Sarah K. Browne,Shrimati Datta,Joshua D. Milner,Douglas B. Kuhns,Debra A. Long Priel,Mohammed A. Sadat,Michael U. Shiloh,Brendan De Marco,Michael Alvares,Jason Gillman,Vivek Ramarathnam,Maria Teresa De La Morena,Liliana Bezrodnik,Ileana Moreira,Gulbu Uzel,Daniel Johnson,Christine Spalding,Christa S. Zerbe,Henry E. Wiley,David E. Greenberg,Susan E. Hoover,Sergio D. Rosenzweig,John N. Galgiani,Steven M. Holland +37 more
TL;DR: Gain-of-function mutations in STAT1 predispose to invasive, severe, disseminated dimorphic yeast infections, likely through aberrant regulation of IFN-γ-mediated inflammation.
Journal ArticleDOI
Markers of Inflammation in Bacterial Diarrhea among Travelers, with a Focus on Enteroaggregative Escherichia coli Pathogenicity
TL;DR: Bacterial pathogens causing traveler's diarrhea commonly produce intestinal inflammation, although a subset of patients with EAEC-associated diarrhea fail to develop an inflammatory response.
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Antibiotic-Induced Depletion of Anti-inflammatory Clostridia Is Associated with the Development of Graft-versus-Host Disease in Pediatric Stem Cell Transplantation Patients
Tiffany Simms-Waldrip,Gauri Sunkersett,Laura A. Coughlin,Milan R. Savani,Carlos Arana,Jiwoong Kim,Min Kim,Xiaowei Zhan,David E. Greenberg,Yang Xie,Stella M. Davies,Andrew Y. Koh +11 more
TL;DR: It is shown that pediatric SCT patients who developed GVHD showed a significant decline, up to 10-log fold, in gut anti-inflammatory Clostridia (AIC) compared with those without GV HD, and this development is significantly associated with cumulative antibiotic exposure.
Journal ArticleDOI
Rate of occurrence and pathogenic effect of enteroaggregative Escherichia coli virulence factors in international travelers.
Zhi-Dong Jiang,David E. Greenberg,James P. Nataro,Robert Steffen,Herbert L. DuPont,Herbert L. DuPont,Herbert L. DuPont +6 more
TL;DR: The different patterns of virulence factors of EAEC revealed several clusters demonstrating diversity among the isolates from the various regions, and the pathogenicity of many strains was suggested by showing an association between the presence of plasmid-borne virulence Factors and the presenceof fecal cytokines.