R
Renata Ochocka
Researcher at Gdańsk Medical University
Publications - 17
Citations - 817
Renata Ochocka is an academic researcher from Gdańsk Medical University. The author has contributed to research in topics: Unfolded protein response & Endoplasmic reticulum. The author has an hindex of 11, co-authored 17 publications receiving 548 citations. Previous affiliations of Renata Ochocka include University of Alabama at Birmingham.
Papers
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Journal ArticleDOI
miRNAs regulate the HIF switch during hypoxia: a novel therapeutic target.
Marcin Serocki,Sylwia Bartoszewska,Anna Janaszak-Jasiecka,Renata Ochocka,James F. Collawn,Rafal Bartoszewski +5 more
TL;DR: The significance of the microRNAs on the relationship between the HIFs under both physiological and pathophysiological conditions is reviewed and miRNAs that endogenously regulate gene expression via the RNA interference pathway are shown to play critical roles in the hypoxia response pathways.
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The hypoxia-inducible miR-429 regulates hypoxia-inducible factor- 1α expression in human endothelial cells through a negative feedback loop
Sylwia Bartoszewska,Kinga Kochan,Arkadiusz Piotrowski,Wojciech Kamysz,Renata Ochocka,James F. Collawn,Rafal Bartoszewski +6 more
TL;DR: RNA‐sequencing‐based transcriptome analysis indicated that inhibition of miRNA‐429 in HUVECs up‐regulated 209 mRNAs, a number of which regulate angiogenesis, and this regulatory network helps explain the Hif‐1 transition to HIF‐2 during chronic hypoxia in endothelial cells.
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Primary endothelial cell–specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia
Rafal Bartoszewski,Adrianna Moszyńska,Marcin Serocki,Aleksandra Cabaj,Andreas Polten,Renata Ochocka,Louis J. Dell'Italia,Sylwia Bartoszewska,Jarosław Króliczewski,Michał Dąbrowski,James F. Collawn +10 more
TL;DR: The studies demonstrate that the switch from HIF‐1 to Hif‐2 constitutes a universal mechanism of cellular adaptation to hypoxic stress and that HIF1A and HIF2A mRNA stability differences contribute to HIF switch.
Journal ArticleDOI
Regulation of angiogenesis by hypoxia: the role of microRNA.
Piotr Madanecki,Niren Kapoor,Zsuzsa Bebok,Renata Ochocka,James F. Collawn,Rafal Bartoszewski +5 more
TL;DR: Although hypoxia and ischemia change the expression profile of many miRNAs, a functional role for a limited number of so-called hypoxamiRs has been demonstrated in angiogenesis and this work discusses the best examples that illustrate the role of hypoxAMIRs inAngiogenesis.
Journal Article
Comparative analysis of phenolic acids in mistletoe plants from various hosts.
TL;DR: Qualitative and quantitative composition of mistletoes hosted by Malus domestica and Pyrus communis showed considerable similarities as far as phenolic acids were concerned and vanillic acid, absent in all other batches of plant material, seemed to be characteristic of the above mistle toes.