EASL-EORTC clinical practice guidelines : management of hepatocellular carcinoma

Background and Aims:The lack of consensus on how to define and grade adverse postoperative events has greatly hampered the evaluation of surgical procedures. A new classification of complications, initiated in 1992, was updated 5 years ago. It is based on the type of therapy needed to correct the co

The Clavien-Dindo classification of surgical complications: five-year experience.

Since the publication of the American Association for the Study of Liver Diseases (AASLD) practice guidelines on the management of hepatocellular carcinoma (HCC) in 2005, new information has emerged that requires that the guidelines be updated. The full version of the new guidelines is available on the AASLD Web site at http://www.aasld.org/practiceguidelines/ Documents/Bookmarked%20Practice%20Guidelines/ HCCUpdate2010.pdf. Here, we briefly describe only new or changed recommendations.

/pdf/aasld-practice-guideline-management-of-hepatocellular-51bocalv0r.pdf

AASLD PRACTICE GUIDELINE Management of Hepatocellular Carcinoma: An Update

Background The role of orthotopic liver transplantation in the treatment of patients with cirrhosis and hepatocellular carcinoma is controversial, and determining which patients are likely to have a good outcome after liver transplantation is difficult. Methods We studied 48 patients with cirrhosis who had small, unresectable hepatocellular carcinomas and who underwent liver transplantation. In 94 percent of the patients, the cirrhosis was related to infection with hepatitis B virus, hepatitis C virus, or both. The presence of tumor was confirmed by biopsy or serum alpha-fetoprotein assay. The criteria for eligibility for transplantation were the presence of a tumor 5 cm or less in diameter in patients with single hepatocellular carcinomas and no more than three tumor nodules, each 3 cm or less in diameter, in patients with multiple tumors. Twenty-eight patients with sufficient hepatic function underwent treatment for the tumor, mainly chemoembolization, before transplantation. After liver transplantation...

Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.20933

Management of hepatocellular carcinoma.

The rex shunt for left portal vein reconstruction during hepatectomy for malignancy using of rex-shunt in adults for oncoliver surgery

The Culture of the Finance Profession: Evidence from the 2020/2021 American Finance Association Survey

Hepatocellular carcinoma (HCC) when left untreated has an extremely poor prognosis Liver transplantation in certain situations has proven benefit despite a high incidence of recurrence, although, survival at 5 years, is still the lowest compared to other indications for transplantation We have, since our initial retrospective report [1], carefully selected patients with a chance for cure based upon the size and number of lesions Subsequently, in this second prospective period, the results of this new approach were reviewed with emphasis on evaluating factors of recurrence and survival for patients with known HCC in cirrhosis

Prevention of recurrence after liver transplantation for hepatocellular carcinoma

Reply to letter: "resection or transplantation for early hepatocellular carcinoma in a cirrhotic liver: does size define the best oncological strategy?".

Background: Liver resections (LR) in liver transplantation recipients (LTR) are extremely rare. The reason for LR in LTR include: management of hepatic artery thrombosis (HAT), ischemic biliary lesions (IBL), liver abscess, liver trauma and recurrence of malignancies (specially hepatocellular carcinoma-HCC). Even though re-transplantation is the treatment of choice for complications like HAT or IBL; organ shortage, increasing time in waiting lists, and the decreased survival after re-transplantation, have encouraged graft-saving procedures. 

René Adam

Papers

The rex shunt for left portal vein reconstruction during hepatectomy for malignancy using of rex-shunt in adults for oncoliver surgery

The Culture of the Finance Profession: Evidence from the 2020/2021 American Finance Association Survey

Prevention of recurrence after liver transplantation for hepatocellular carcinoma

Reply to letter: "resection or transplantation for early hepatocellular carcinoma in a cirrhotic liver: does size define the best oncological strategy?".

Recurrent HCC: First indication for liver resections in liver transplantation recipients - 39 years of experience at an international reference center